ID   ANGT_VIBA7              Reviewed;         252 AA.
AC   Q6W4T2; P19829;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Probable anguibactin biosynthesis thioesterase AngT;
DE            EC=3.1.2.-;
GN   Name=angT;
OS   Vibrio anguillarum (strain ATCC 68554 / 775) (Listonella anguillarum).
OG   Plasmid pJM1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=882102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 68554 / 775;
RX   PubMed=2311935; DOI=10.1016/0378-1119(90)90112-5;
RA   Farrell D.H., Mikesell P., Actis L.A., Crosa J.H.;
RT   "A regulatory gene, angR, of the iron uptake system of Vibrio anguillarum:
RT   similarity with phage P22 cro and regulation by iron.";
RL   Gene 86:45-51(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 68554 / 775;
RX   PubMed=13129954; DOI=10.1128/jb.185.19.5822-5830.2003;
RA   Di Lorenzo M., Stork M., Tolmasky M.E., Actis L.A., Farrell D., Welch T.J.,
RA   Crosa L.M., Wertheimer A.M., Chen Q., Salinas P., Waldbeser L., Crosa J.H.;
RT   "Complete sequence of virulence plasmid pJM1 from the marine fish pathogen
RT   Vibrio anguillarum strain 775.";
RL   J. Bacteriol. 185:5822-5830(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 68554 / 775;
RX   PubMed=21576332; DOI=10.1128/iai.05138-11;
RA   Naka H., Dias G.M., Thompson C.C., Dubay C., Thompson F.L., Crosa J.H.;
RT   "Complete genome sequence of the marine fish pathogen Vibrio anguillarum
RT   harboring the pJM1 virulence plasmid and genomic comparison with other
RT   virulent strains of V. anguillarum and V. ordalii.";
RL   Infect. Immun. 79:2889-2900(2011).
RN   [4]
RP   FUNCTION, PATHWAY, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 68554 / 775;
RX   PubMed=10569768; DOI=10.1128/iai.67.12.6496-6509.1999;
RA   Wertheimer A.M., Verweij W., Chen Q., Crosa L.M., Nagasawa M.,
RA   Tolmasky M.E., Actis L.A., Crosa J.H.;
RT   "Characterization of the angR gene of Vibrio anguillarum: essential role in
RT   virulence.";
RL   Infect. Immun. 67:6496-6509(1999).
CC   -!- FUNCTION: Probable thioesterase. Involved in anguibactin production,
CC       but is not essential for virulence or iron transport gene expression.
CC       {ECO:0000269|PubMed:10569768}.
CC   -!- PATHWAY: Siderophore biosynthesis; anguibactin biosynthesis.
CC       {ECO:0000269|PubMed:10569768}.
CC   -!- DISRUPTION PHENOTYPE: Deletion results in a decrease of anguibactin
CC       production and in a moderate attenuation of virulence.
CC       {ECO:0000269|PubMed:10569768}.
CC   -!- SIMILARITY: Belongs to the thioesterase family. {ECO:0000305}.
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DR   EMBL; M34504; AAA79861.1; -; Genomic_DNA.
DR   EMBL; AY312585; AAR12529.1; -; Genomic_DNA.
DR   PIR; JQ0417; JQ0417.
DR   RefSeq; NP_943554.1; NC_005250.1.
DR   RefSeq; WP_011154640.1; NC_005250.1.
DR   AlphaFoldDB; Q6W4T2; -.
DR   SMR; Q6W4T2; -.
DR   eggNOG; COG3208; Bacteria.
DR   OMA; KREVIAM; -.
DR   UniPathway; UPA00016; -.
DR   Proteomes; UP000006800; Plasmid pJM1.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR012223; TEII.
DR   InterPro; IPR001031; Thioesterase.
DR   PANTHER; PTHR11487; PTHR11487; 1.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Plasmid; Virulence.
FT   CHAIN           1..252
FT                   /note="Probable anguibactin biosynthesis thioesterase AngT"
FT                   /id="PRO_0000417118"
FT   ACT_SITE        92
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        229
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   252 AA;  28070 MW;  1FB1AA3CCEDB99F4 CRC64;
     MSPLIKLAAS SRLHDATHYV LCPFAGGGSG AFRHWRTLSL ENEVISVMLY PGREFRIDDP
     TVINIGTLAE EMIQALKTCN QRIEDTIIVG HSMGAQVAYE ASKKLVNQGL FLKGLIISGC
     QAPHIKGRRL LGECDDKTFI HNLVEIGGCD PSLAKSPEWW PIFLPALRAD FTATEQYIFT
     SLPNDKEGLP IPTLLISGDQ DREANFSEIE EWKLWCNKVV DHLVVEGGHF YITEQPQMML
     ECIRALSTET TA