ID   ANKR7_MOUSE             Reviewed;         279 AA.
AC   Q9D504; Q810N2; Q8BVP4;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Ankyrin repeat domain-containing protein 7;
GN   Name=Ankrd7;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AK015948; BAB30047.1; -; mRNA.
DR   EMBL; AK077080; BAC36600.1; -; mRNA.
DR   EMBL; BC049731; AAH49731.1; -; mRNA.
DR   CCDS; CCDS19933.1; -.
DR   RefSeq; NP_001161229.1; NM_001167757.1.
DR   RefSeq; NP_083478.2; NM_029202.2.
DR   AlphaFoldDB; Q9D504; -.
DR   SMR; Q9D504; -.
DR   BioGRID; 217294; 2.
DR   IntAct; Q9D504; 2.
DR   iPTMnet; Q9D504; -.
DR   PhosphoSitePlus; Q9D504; -.
DR   PaxDb; Q9D504; -.
DR   PRIDE; Q9D504; -.
DR   ProteomicsDB; 296246; -.
DR   DNASU; 75196; -.
DR   Ensembl; ENSMUST00000031489; ENSMUSP00000031489; ENSMUSG00000029517.
DR   GeneID; 75196; -.
DR   KEGG; mmu:75196; -.
DR   UCSC; uc009bap.1; mouse.
DR   CTD; 56311; -.
DR   MGI; MGI:1922446; Ankrd7.
DR   VEuPathDB; HostDB:ENSMUSG00000029517; -.
DR   eggNOG; KOG0504; Eukaryota.
DR   GeneTree; ENSGT00940000161777; -.
DR   InParanoid; Q9D504; -.
DR   OrthoDB; 1514637at2759; -.
DR   PhylomeDB; Q9D504; -.
DR   TreeFam; TF337879; -.
DR   BioGRID-ORCS; 75196; 2 hits in 72 CRISPR screens.
DR   ChiTaRS; Ankrd7; mouse.
DR   PRO; PR:Q9D504; -.
DR   Proteomes; UP000000589; Chromosome 6.
DR   RNAct; Q9D504; protein.
DR   Bgee; ENSMUSG00000029517; Expressed in spermatid and 3 other tissues.
DR   ExpressionAtlas; Q9D504; baseline and differential.
DR   Genevisible; Q9D504; MM.
DR   GO; GO:0005813; C:centrosome; ISO:MGI.
DR   GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR   GO; GO:0005634; C:nucleus; IDA:MGI.
DR   GO; GO:0001835; P:blastocyst hatching; IMP:MGI.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   Pfam; PF12796; Ank_2; 2.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 5.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 4.
PE   2: Evidence at transcript level;
KW   ANK repeat; Reference proteome; Repeat.
FT   CHAIN           1..279
FT                   /note="Ankyrin repeat domain-containing protein 7"
FT                   /id="PRO_0000320067"
FT   REPEAT          80..109
FT                   /note="ANK 1"
FT   REPEAT          113..142
FT                   /note="ANK 2"
FT   REPEAT          146..175
FT                   /note="ANK 3"
FT   REPEAT          179..208
FT                   /note="ANK 4"
FT   REPEAT          212..241
FT                   /note="ANK 5"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        34
FT                   /note="S -> N (in Ref. 1; BAB30047)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        42
FT                   /note="H -> R (in Ref. 1; BAB30047)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        78
FT                   /note="D -> G (in Ref. 2; AAH49731)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        120
FT                   /note="K -> KQ (in Ref. 1; BAC36600)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   279 AA;  31202 MW;  C98F99E7323A428C CRC64;
     MKKFFPFRGK RKTDDSHSHS SEVPISLAKT APPSLSIGGG YHLRDKHLKK LHKAATIGNE
     QKLKDYLERK KYNVNGRDKR SRTPLHLACA NGYTNIVSLL IENQCKINVQ DSENRTPLIK
     AVECQQESCA TVLLLHGADP NLVDVYSNTA LHYAVCGQNI SLANKLLQYK ANLEAKNKDG
     HTPLLLAVAE NNENMVKFLL KKGADVNASD KNHRTAIMIA LIVEPTSSVK LLLQQDTDLA
     HKDIYGFTAE EYASFNGFTM YHHITANNEN KKKTEQTAY