ID   ANM1_ORYSI              Reviewed;         387 AA.
AC   A2Z0C0;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Probable protein arginine N-methyltransferase 1;
DE            EC=2.1.1.-;
GN   Name=PRMT1; ORFNames=OsI_030013;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Methylates (mono and asymmetric dimethylation) the guanidino
CC       nitrogens of arginyl residues present in a glycine and arginine-rich
CC       domain (can methylate histones). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. Protein arginine N-methyltransferase family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01015}.
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DR   EMBL; CM000134; EAZ08781.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2Z0C0; -.
DR   SMR; A2Z0C0; -.
DR   STRING; 39946.A2Z0C0; -.
DR   iPTMnet; A2Z0C0; -.
DR   EnsemblPlants; BGIOSGA029907-TA; BGIOSGA029907-PA; BGIOSGA029907.
DR   Gramene; BGIOSGA029907-TA; BGIOSGA029907-PA; BGIOSGA029907.
DR   HOGENOM; CLU_017375_1_2_1; -.
DR   OMA; RNDFVHA; -.
DR   Proteomes; UP000007015; Chromosome 9.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0018216; P:peptidyl-arginine methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR11006; PTHR11006; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS51678; SAM_MT_PRMT; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Nucleus; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..387
FT                   /note="Probable protein arginine N-methyltransferase 1"
FT                   /id="PRO_0000293988"
FT   DOMAIN          66..387
FT                   /note="SAM-dependent MTase PRMT-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01015"
FT   REGION          1..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        178
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        187
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   387 AA;  43014 MW;  DB36D4628EF4BA63 CRC64;
     MDQRKGSGSD ANGGLAEATA SRLRFEDPDE VMEENPAAAA ATVGAEEEGG EGGGGEEVIG
     SDKTSADYYF DSYSHFGIHE EMLKDVVRTK SYQNVITQNS FLFKDKIVLD VGAGTGILSL
     FCAKAGAKHV YAIECSQMAD MAKEIVKTNG YSNVITVIKG KVEEIELPVP KVDVIISEWM
     GYFLLFENML NTVLYARDKW LADGGVVLPD KASLHLTAIE DAEYKEDKIE FWNNVYGFDM
     RCIKKQAMME PLVDTVDANQ IVTNCQLLKT MDISKMTPGD ASFTVPFKLV AERNDYIHAL
     VAYFNVSFTK CHKMMGFSTG PRSKATHWKQ TVLYLEDVLT ICEGETITGS MTVTPNKKNP
     RDIDIKLCYA LSGHRCQVSR TQHYKMR