ID   ANM1_ORYSJ              Reviewed;         387 AA.
AC   Q0J2C6; A3BY04; B7EPL4; Q6K563;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Probable protein arginine N-methyltransferase 1;
DE            EC=2.1.1.-;
GN   Name=PRMT1; OrderedLocusNames=Os09g0359800, LOC_Os09g19560;
GN   ORFNames=OsJ_027926, P0711F01.27-1;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- FUNCTION: Methylates (mono and asymmetric dimethylation) the guanidino
CC       nitrogens of arginyl residues present in a glycine and arginine-rich
CC       domain (can methylate histones). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. Protein arginine N-methyltransferase family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01015}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD23315.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=EAZ44443.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP005508; BAD23315.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008215; BAF24889.1; -; Genomic_DNA.
DR   EMBL; AP014965; BAT07684.1; -; Genomic_DNA.
DR   EMBL; CM000146; EAZ44443.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AK099826; BAG94311.1; -; mRNA.
DR   RefSeq; XP_015612441.1; XM_015756955.1.
DR   AlphaFoldDB; Q0J2C6; -.
DR   SMR; Q0J2C6; -.
DR   STRING; 4530.OS09T0359800-01; -.
DR   PaxDb; Q0J2C6; -.
DR   PRIDE; Q0J2C6; -.
DR   EnsemblPlants; Os09t0359800-01; Os09t0359800-01; Os09g0359800.
DR   GeneID; 4346843; -.
DR   Gramene; Os09t0359800-01; Os09t0359800-01; Os09g0359800.
DR   KEGG; osa:4346843; -.
DR   eggNOG; KOG1499; Eukaryota.
DR   HOGENOM; CLU_017375_1_2_1; -.
DR   InParanoid; Q0J2C6; -.
DR   OMA; RNDFVHA; -.
DR   OrthoDB; 840669at2759; -.
DR   Proteomes; UP000000763; Chromosome 9.
DR   Proteomes; UP000007752; Chromosome 9.
DR   Proteomes; UP000059680; Chromosome 9.
DR   ExpressionAtlas; Q0J2C6; baseline and differential.
DR   Genevisible; Q0J2C6; OS.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0018216; P:peptidyl-arginine methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR11006; PTHR11006; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS51678; SAM_MT_PRMT; 1.
PE   2: Evidence at transcript level;
KW   Methyltransferase; Nucleus; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..387
FT                   /note="Probable protein arginine N-methyltransferase 1"
FT                   /id="PRO_0000293989"
FT   DOMAIN          66..387
FT                   /note="SAM-dependent MTase PRMT-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01015"
FT   REGION          1..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        178
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        187
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   387 AA;  43014 MW;  DB36D4628EF4BA63 CRC64;
     MDQRKGSGSD ANGGLAEATA SRLRFEDPDE VMEENPAAAA ATVGAEEEGG EGGGGEEVIG
     SDKTSADYYF DSYSHFGIHE EMLKDVVRTK SYQNVITQNS FLFKDKIVLD VGAGTGILSL
     FCAKAGAKHV YAIECSQMAD MAKEIVKTNG YSNVITVIKG KVEEIELPVP KVDVIISEWM
     GYFLLFENML NTVLYARDKW LADGGVVLPD KASLHLTAIE DAEYKEDKIE FWNNVYGFDM
     RCIKKQAMME PLVDTVDANQ IVTNCQLLKT MDISKMTPGD ASFTVPFKLV AERNDYIHAL
     VAYFNVSFTK CHKMMGFSTG PRSKATHWKQ TVLYLEDVLT ICEGETITGS MTVTPNKKNP
     RDIDIKLCYA LSGHRCQVSR TQHYKMR