ID   HEMS_YEREN              Reviewed;         345 AA.
AC   P31517;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Hemin transport protein HemS;
GN   Name=hemS;
OS   Yersinia enterocolitica.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 51872 / WA-C / Serotype O:8;
RX   PubMed=7997183; DOI=10.1111/j.1365-2958.1994.tb00465.x;
RA   Stojiljkovic I., Hantke K.;
RT   "Transport of haemin across the cytoplasmic membrane through a haemin-
RT   specific periplasmic binding-protein-dependent transport system in Yersinia
RT   enterocolitica.";
RL   Mol. Microbiol. 13:719-732(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-25.
RC   STRAIN=ATCC 51872 / WA-C / Serotype O:8;
RX   PubMed=1425573; DOI=10.1002/j.1460-2075.1992.tb05535.x;
RA   Stojiljkovic I., Hantke K.;
RT   "Hemin uptake system of Yersinia enterocolitica: similarities with other
RT   TonB-dependent systems in Gram-negative bacteria.";
RL   EMBO J. 11:4359-4367(1992).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       hemin.
CC   -!- SIMILARITY: To Y.pestis HmuS. {ECO:0000305}.
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DR   EMBL; X77867; CAA54865.1; -; Genomic_DNA.
DR   EMBL; X68147; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; S54436; S54436.
DR   PDB; 2J0P; X-ray; 1.70 A; A=1-345.
DR   PDB; 2J0R; X-ray; 1.90 A; A=1-345.
DR   PDBsum; 2J0P; -.
DR   PDBsum; 2J0R; -.
DR   AlphaFoldDB; P31517; -.
DR   SMR; P31517; -.
DR   STRING; 1443113.LC20_04858; -.
DR   eggNOG; COG3720; Bacteria.
DR   EvolutionaryTrace; P31517; -.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR   InterPro; IPR007845; HemS/ChuX_dom.
DR   Pfam; PF05171; HemS; 2.
PE   1: Evidence at protein level;
KW   3D-structure; Ion transport; Iron; Iron transport; Transport.
FT   CHAIN           1..345
FT                   /note="Hemin transport protein HemS"
FT                   /id="PRO_0000083948"
FT   HELIX           5..14
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           21..27
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           32..39
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   TURN            40..42
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          43..47
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           51..57
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           58..61
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          64..69
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          71..79
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          83..85
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          87..93
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          101..104
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           105..107
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          108..118
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          121..130
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          135..140
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           147..157
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          158..160
FT                   /evidence="ECO:0007829|PDB:2J0R"
FT   HELIX           182..191
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           195..197
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           198..204
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           209..215
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   TURN            218..220
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          221..224
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           228..239
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          243..248
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          250..258
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          263..266
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          269..273
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          275..282
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           283..285
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          288..294
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          301..307
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   STRAND          313..319
FT                   /evidence="ECO:0007829|PDB:2J0P"
FT   HELIX           329..335
FT                   /evidence="ECO:0007829|PDB:2J0P"
SQ   SEQUENCE   345 AA;  39201 MW;  3724A695FA950774 CRC64;
     MSKSIYEQYL QAKADNPGKY ARDLATLMGI SEAELTHSRV SHDAKRLKGD ARALLAALEA
     VGEVKAITRN TYAVHEQMGR YENQHLNGHA GLILNPRNLD LRLFLNQWAS AFTLTEETRH
     GVRHSIQFFD HQGDALHKVY VTEQTDMPAW EALLAQFITT EIPELQLEPL SAPEVTEPTA
     TDEAVDAEWR AMTDVHQFFQ LLKRNNLTRQ QAFRAVGNDL AYQVDNSSLT QLLNIAQQEQ
     NEIMIFVGNR GCVQIFTGMI EKVTPHQDWI NVFNQRFTLH LIETTIAESW ITRKPTKDGF
     VTSLELFAAD GTQIAQLYGQ RTEGQPEQTQ WRDEIARLNN KDIAA