ID   HEMTB_AQUAE             Reviewed;         131 AA.
AC   O67614;
DT   27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Bacteriohemerythrin {ECO:0000255|HAMAP-Rule:MF_00556};
GN   OrderedLocusNames=aq_1719;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Oxygen-binding protein. May be involved in a storage
CC       mechanism or for delivery to oxygen-requiring enzymes. The oxygen-
CC       binding site contains two iron atoms. {ECO:0000255|HAMAP-
CC       Rule:MF_00556}.
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00556}.
CC   -!- SIMILARITY: Belongs to the hemerythrin family. {ECO:0000255|HAMAP-
CC       Rule:MF_00556}.
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DR   EMBL; AE000657; AAC07584.1; -; Genomic_DNA.
DR   PIR; D70448; D70448.
DR   RefSeq; NP_214180.1; NC_000918.1.
DR   RefSeq; WP_010881117.1; NC_000918.1.
DR   AlphaFoldDB; O67614; -.
DR   SMR; O67614; -.
DR   STRING; 224324.aq_1719; -.
DR   EnsemblBacteria; AAC07584; AAC07584; aq_1719.
DR   KEGG; aae:aq_1719; -.
DR   PATRIC; fig|224324.8.peg.1322; -.
DR   eggNOG; COG2703; Bacteria.
DR   HOGENOM; CLU_086902_1_3_0; -.
DR   InParanoid; O67614; -.
DR   OMA; MDTVTAM; -.
DR   OrthoDB; 1991725at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-UniRule.
DR   CDD; cd12107; Hemerythrin; 1.
DR   Gene3D; 1.20.120.50; -; 1.
DR   HAMAP; MF_00556; Hemerythrin; 1.
DR   InterPro; IPR023504; Bacteriohemerythrin-like.
DR   InterPro; IPR016131; Haemerythrin_Fe_BS.
DR   InterPro; IPR012312; Hemerythrin-like.
DR   InterPro; IPR035938; Hemerythrin-like_sf.
DR   InterPro; IPR012827; Hemerythrin_metal-bd.
DR   Pfam; PF01814; Hemerythrin; 1.
DR   SUPFAM; SSF47188; SSF47188; 1.
DR   TIGRFAMs; TIGR02481; hemeryth_dom; 1.
DR   PROSITE; PS00550; HEMERYTHRINS; 1.
PE   3: Inferred from homology;
KW   Iron; Metal-binding; Oxygen transport; Reference proteome; Transport.
FT   CHAIN           1..131
FT                   /note="Bacteriohemerythrin"
FT                   /id="PRO_0000191845"
FT   BINDING         20
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         23
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         56
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         60
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         60
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         75
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         79
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         117
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         122
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
FT   BINDING         122
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00556"
SQ   SEQUENCE   131 AA;  15964 MW;  1494DD8CDFAB235C CRC64;
     MLIRPNKVQK VGNLFMDTVH EEEIRLLNQL YDTLMKKDVE KADQLMDELL VDLEDHFTTE
     EELMREFEFF AYPMHKAEHD TMRKRFKEVY DKWKKEKNPE EVVRFLKEEF VPWLKSHVAR
     WDSTTAQQLG D