ID   HEMTL_NEMVE             Reviewed;         156 AA.
AC   A7T0T1;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Hemerythrin-like protein;
GN   ORFNames=v1g220584;
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6;
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- FUNCTION: Oxygen-binding protein. The oxygen-binding site contains two
CC       iron atoms (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the hemerythrin family. {ECO:0000305}.
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DR   EMBL; DS470049; EDO30441.1; -; Genomic_DNA.
DR   RefSeq; XP_001622541.1; XM_001622491.1.
DR   AlphaFoldDB; A7T0T1; -.
DR   SMR; A7T0T1; -.
DR   EnsemblMetazoa; EDO30441; EDO30441; NEMVEDRAFT_v1g220584.
DR   eggNOG; ENOG502SW2H; Eukaryota.
DR   HOGENOM; CLU_086902_4_0_1; -.
DR   InParanoid; A7T0T1; -.
DR   OMA; ACPVAND; -.
DR   OrthoDB; 1580951at2759; -.
DR   PhylomeDB; A7T0T1; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.50; -; 1.
DR   InterPro; IPR002063; Haemerythrin.
DR   InterPro; IPR035938; Hemerythrin-like_sf.
DR   PRINTS; PR00186; HEMERYTHRIN.
DR   SUPFAM; SSF47188; SSF47188; 1.
PE   3: Inferred from homology;
KW   Iron; Metal-binding; Oxygen transport; Reference proteome; Transport.
FT   CHAIN           1..156
FT                   /note="Hemerythrin-like protein"
FT                   /id="PRO_0000343359"
FT   BINDING         54
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         84
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         88
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         88
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         109
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         113
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         142
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         147
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         147
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
SQ   SEQUENCE   156 AA;  17762 MW;  036A154BF4FC8EEC CRC64;
     MGLPPIECPF DIPKPFRHPD LFDKFSNCDP LPIFFLNRWN ESFKVFYQNL DDEHRGLFDV
     VFDVDAKRGD AGAVSKAASA FKGHFTTEEA EMKKGVDAGK LDGAHYKGHC TAHNKFLELF
     GSFGNNLGDD EINYSMKWLV NHIKSTDFHY KGKLIQ