ID   HEMTM_RIFPA             Reviewed;         120 AA.
AC   A8STG1;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Myohemerythrin;
DE            Short=MHr;
OS   Riftia pachyptila (Vent tube worm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC   Sedentaria; Canalipalpata; Sabellida; Siboglinidae; Riftia.
OX   NCBI_TaxID=6426;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=17892591; DOI=10.1186/1471-2164-8-337;
RA   Sanchez S., Hourdez S., Lallier F.H.;
RT   "Identification of proteins involved in the functioning of Riftia
RT   pachyptila symbiosis by Subtractive Suppression Hybridization.";
RL   BMC Genomics 8:337-337(2007).
CC   -!- FUNCTION: Myohemerythrin is an oxygen-binding protein found in the
CC       retractor muscles of certain worms. The oxygen-binding site contains
CC       two iron atoms (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the hemerythrin family. {ECO:0000305}.
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DR   EMBL; EF648563; ABW24415.1; -; mRNA.
DR   AlphaFoldDB; A8STG1; -.
DR   SMR; A8STG1; -.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProt.
DR   CDD; cd12107; Hemerythrin; 1.
DR   Gene3D; 1.20.120.50; -; 1.
DR   InterPro; IPR002063; Haemerythrin.
DR   InterPro; IPR016131; Haemerythrin_Fe_BS.
DR   InterPro; IPR012312; Hemerythrin-like.
DR   InterPro; IPR035938; Hemerythrin-like_sf.
DR   InterPro; IPR012827; Hemerythrin_metal-bd.
DR   Pfam; PF01814; Hemerythrin; 1.
DR   PIRSF; PIRSF002033; Hemerythrin; 1.
DR   PRINTS; PR00186; HEMERYTHRIN.
DR   SUPFAM; SSF47188; SSF47188; 1.
DR   TIGRFAMs; TIGR02481; hemeryth_dom; 1.
DR   TIGRFAMs; TIGR00058; Hemerythrin; 1.
DR   PROSITE; PS00550; HEMERYTHRINS; 1.
PE   2: Evidence at transcript level;
KW   Iron; Metal-binding; Muscle protein; Oxygen transport; Transport.
FT   CHAIN           1..120
FT                   /note="Myohemerythrin"
FT                   /id="PRO_0000343355"
FT   BINDING         26
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         56
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         60
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         60
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         75
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         79
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         108
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         113
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
FT   BINDING         113
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P02244"
SQ   SEQUENCE   120 AA;  13505 MW;  95CE3F55D6452308 CRC64;
     MSFEVPSPYV WDDSFRVAYD NLDSEHQALF KCIAKCAENR ADAAALADLV KVTVDHFADE
     ERMMAKTNFS GLPEHNKIHS EFVAKIKSLS APLDDATVAF AKQWLVNHIK GIDFKYKGNL