ID   HESA_NOSS1              Reviewed;         252 AA.
AC   P18500;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 2.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Protein HesA;
GN   Name=hesA; OrderedLocusNames=all1432;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2115111; DOI=10.1007/bf00261725;
RA   Borthakur D., Basche M., Buikema W.J., Borthakur P.B., Haselkorn R.;
RT   "Expression, nucleotide sequence and mutational analysis of two open
RT   reading frames in the nif gene region of Anabaena sp. strain PCC7120.";
RL   Mol. Gen. Genet. 221:227-234(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: May be required for efficient nitrogen fixation.
CC   -!- SIMILARITY: Belongs to the HesA/MoeB/ThiF family. {ECO:0000305}.
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DR   EMBL; X15553; CAA33558.1; -; Genomic_DNA.
DR   EMBL; BA000019; BAB73389.1; -; Genomic_DNA.
DR   PIR; AE1985; AE1985.
DR   PIR; S11900; S11900.
DR   AlphaFoldDB; P18500; -.
DR   SMR; P18500; -.
DR   STRING; 103690.17130779; -.
DR   EnsemblBacteria; BAB73389; BAB73389; BAB73389.
DR   KEGG; ana:all1432; -.
DR   eggNOG; COG0476; Bacteria.
DR   OMA; SAKWKLE; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR10953; PTHR10953; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; SSF69572; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation; Reference proteome.
FT   CHAIN           1..252
FT                   /note="Protein HesA"
FT                   /id="PRO_0000120570"
FT   CONFLICT        233..252
FT                   /note="APWRYAQSNSMETSSNCTHS -> RLGDMHNPIQWKPAVIAHIVDTNANHYK
FT                   HHTLKT (in Ref. 1; CAA33558)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   252 AA;  27676 MW;  515F42A9A0B20880 CRC64;
     MMLPNFGEAA QKRLKSATVL VTGVGGLGGT AALYLAVAGV GRLILVRGGD LRLDDMNRQV
     LMTDDWVGKP RVFKAKETLQ AINPDIQIET IHDYITSENV DSLVQSADMA LDCAHNFTER
     DLLNSACVRW RKPMVEAAMD GMEAYLTTII PGVTPCLSCI FPEKPDWDRR GFSVLGAVSG
     TLACLTALEA IKLITGFSQP LLSQLLTIDL NRMEFAKRRL YRDRSCPVCG NDAPWRYAQS
     NSMETSSNCT HS