ID   HEXA_ARTBC              Reviewed;         353 AA.
AC   D4AQ52;
DT   11-NOV-2015, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Uncharacterized secreted glycosyl hydrolase ARB_06359 {ECO:0000305};
DE            EC=3.2.1.- {ECO:0000305};
DE   Flags: Precursor;
GN   ORFNames=ARB_06359;
OS   Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS   mentagrophytes).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4681 / CBS 112371;
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA   Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA   Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA   Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=21919205; DOI=10.1002/pmic.201100234;
RA   Sriranganadane D., Waridel P., Salamin K., Feuermann M., Mignon B.,
RA   Staib P., Neuhaus J.M., Quadroni M., Monod M.;
RT   "Identification of novel secreted proteases during extracellular
RT   proteolysis by dermatophytes at acidic pH.";
RL   Proteomics 11:4422-4433(2011).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21919205}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family. {ECO:0000305}.
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DR   EMBL; ABSU01000005; EFE34596.1; -; Genomic_DNA.
DR   RefSeq; XP_003015236.1; XM_003015190.1.
DR   AlphaFoldDB; D4AQ52; -.
DR   SMR; D4AQ52; -.
DR   STRING; 663331.D4AQ52; -.
DR   PRIDE; D4AQ52; -.
DR   EnsemblFungi; EFE34596; EFE34596; ARB_06359.
DR   GeneID; 9520960; -.
DR   KEGG; abe:ARB_06359; -.
DR   eggNOG; ENOG502SJNP; Eukaryota.
DR   HOGENOM; CLU_008392_0_1_1; -.
DR   OMA; WQMAAEM; -.
DR   Proteomes; UP000008866; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.300; -; 1.
DR   InterPro; IPR001764; Glyco_hydro_3_N.
DR   InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00933; Glyco_hydro_3; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Glycosidase; Hydrolase; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..353
FT                   /note="Uncharacterized secreted glycosyl hydrolase
FT                   ARB_06359"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000434661"
FT   REGION          94..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        165
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        312
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ   SEQUENCE   353 AA;  37598 MW;  1E12DCF12B71B332 CRC64;
     MKFVLFAQLA AVAAPAIAID LAVQAGQHVM YSYPGLTPPE SLYKLTSEGK VGGLIIFKEN
     VNSNLPAIMD KFQALYKASP AYNGHPMIIT TDQEGGNVRR VPGGPSQSAR QIGDSSTPMQ
     AASQAGRDAA AALKAQKING NLAPVLDIYR EEGNFIDEFG RSFGNNTEIV TSCGSAFAIS
     QSRSGVLSTV KHFPGLGAAK KGENTDLVPI KIDLSLDEIR TFDEVPYRTA IRNGVDLIMT
     SWAVYPSLDA KYPAGLSRKW TTDELRTRLG YKGVIITDAI EAGSLKSFGN DGQRGVLAAK
     AGVDILLASG RNATQGEAIV NEIVAALKKG TLSMTEFQES SKRIQALQSR LSA