HEZ_DROME
ID HEZ_DROME Reviewed; 186 AA.
AC Q9VT67; A8JNP9; Q4V5R7; Q4V5V2; Q4V5X6;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Protein Hezron {ECO:0000312|FlyBase:FBgn0036057};
DE AltName: Full=Protein LSM12 homolog B {ECO:0000305};
GN Name=Hez {ECO:0000312|FlyBase:FBgn0036057};
GN ORFNames=CG14164 {ECO:0000312|FlyBase:FBgn0036057};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 24-186.
RC STRAIN=Berkeley;
RA Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A., Pacleb J.M.,
RA Park S., Wan K.H., Yu C., Celniker S.E.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- MISCELLANEOUS: This protein is produced by a bicistronic gene which
CC also produces the CG6709 protein from a non-overlapping reading frame.
CC -!- SIMILARITY: Belongs to the LSM12 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAY54970.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AE014296; AAF50187.1; -; Genomic_DNA.
DR EMBL; AE014296; ABW08509.1; -; Genomic_DNA.
DR EMBL; BT022530; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BT022554; AAY54970.1; ALT_FRAME; mRNA.
DR EMBL; BT022589; AAY55005.1; -; mRNA.
DR RefSeq; NP_001097566.1; NM_001104096.2.
DR RefSeq; NP_648371.1; NM_140114.3.
DR AlphaFoldDB; Q9VT67; -.
DR BioGRID; 64554; 2.
DR IntAct; Q9VT67; 3.
DR STRING; 7227.FBpp0112070; -.
DR PaxDb; Q9VT67; -.
DR PRIDE; Q9VT67; -.
DR EnsemblMetazoa; FBtr0076359; FBpp0076088; FBgn0036057.
DR EnsemblMetazoa; FBtr0113157; FBpp0112070; FBgn0036057.
DR GeneID; 39167; -.
DR KEGG; dme:Dmel_CG14164; -.
DR UCSC; CG14164-RA; d. melanogaster.
DR UCSC; CG14164-RB; d. melanogaster.
DR CTD; 39167; -.
DR FlyBase; FBgn0036057; Hez.
DR VEuPathDB; VectorBase:FBgn0036057; -.
DR eggNOG; KOG4401; Eukaryota.
DR GeneTree; ENSGT00390000006956; -.
DR HOGENOM; CLU_073383_2_0_1; -.
DR InParanoid; Q9VT67; -.
DR OMA; VRCKTCF; -.
DR PhylomeDB; Q9VT67; -.
DR BioGRID-ORCS; 39167; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 39167; -.
DR PRO; PR:Q9VT67; -.
DR Proteomes; UP000000803; Chromosome 3L.
DR Bgee; FBgn0036057; Expressed in testis and 10 other tissues.
DR Genevisible; Q9VT67; DM.
DR InterPro; IPR019181; Anticodon-binding_dom.
DR InterPro; IPR039683; Lsm12-like.
DR PANTHER; PTHR13542; PTHR13542; 1.
DR Pfam; PF09793; AD; 1.
DR SMART; SM00995; AD; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..186
FT /note="Protein Hezron"
FT /id="PRO_0000305135"
FT CONFLICT 36
FT /note="Missing (in Ref. 3; AAY55005)"
FT /evidence="ECO:0000305"
FT CONFLICT 176
FT /note="E -> G (in Ref. 3; AAY55005/AAY54970)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 186 AA; 20802 MW; B0DE4B21BE5A2CC7 CRC64;
MSSLAPCFTV GSIVRCKTCF GDNISGEVVA FDLGVKMLIM KCPSSNGGGD EQTTCNVTIV
NLSLCMDIEI VKEAIPPAEV QQPEPIDLPM IRERYRYATE HRTLSCRSYH PNASPFGQAL
FRLLVKRFGD PAIIWQNKGD QVAINILRQV VIDAPYATEN IRYLDWNPKL AICVQEVVQN
FCSKQF
