HFB4B_ORYSJ
ID HFB4B_ORYSJ Reviewed; 310 AA.
AC Q7XHZ0; B7E985; Q7XHZ1;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Heat stress transcription factor B-4b;
DE AltName: Full=Heat stress transcription factor 12;
DE Short=OsHSF12;
DE Short=rHsf12;
DE AltName: Full=Heat stress transcription factor 19;
DE Short=OsHsf-19;
GN Name=HSFB4B; Synonyms=HSF12, HSF19;
GN OrderedLocusNames=Os07g0640900, LOC_Os07g44690;
GN ORFNames=OJ1340_C08.141-1, OJ1340_C08.141-2, P0524G08.108-1,
GN P0524G08.108-2;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND FUNCTION.
RX PubMed=16202242; DOI=10.5483/bmbrep.2005.38.5.602;
RA Liu J.-G., Yao Q.-H., Zhang Z., Peng R.-H., Xiong A.-S., Xu F., Zhu H.;
RT "Isolation and characterization of a cDNA encoding two novel heat-shock
RT factor OsHSF6 and OsHSF12 in Oryza sativa L.";
RL J. Biochem. Mol. Biol. 38:602-608(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15625403; DOI=10.1007/bf02712120;
RA Baniwal S.K., Bharti K., Chan K.Y., Fauth M., Ganguli A., Kotak S.,
RA Mishra S.K., Nover L., Port M., Scharf K.-D., Tripp J., Weber C.,
RA Zielinski D., von Koskull-Doering P.;
RT "Heat stress response in plants: a complex game with chaperones and more
RT than twenty heat stress transcription factors.";
RL J. Biosci. 29:471-487(2004).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18407058; DOI=10.1016/s1673-8527(08)60016-8;
RA Guo J., Wu J., Ji Q., Wang C., Luo L., Yuan Y., Wang Y., Wang J.;
RT "Genome-wide analysis of heat shock transcription factor families in rice
RT and Arabidopsis.";
RL J. Genet. Genomics 35:105-118(2008).
CC -!- FUNCTION: Transcriptional activator that specifically binds DNA of heat
CC shock promoter elements (HSE). {ECO:0000269|PubMed:16202242}.
CC -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC -!- INTERACTION:
CC Q7XHZ0; Q7XHZ0: HSFB4B; NbExp=3; IntAct=EBI-7005709, EBI-7005709;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q7XHZ0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q7XHZ0-2; Sequence=VSP_035450, VSP_035451;
CC -!- DOMAIN: The hydrophobic-rich region (HR-A/B) corresponds to the
CC oligomerization domain.
CC -!- PTM: Exhibits temperature-dependent phosphorylation. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the HSF family. Class B subfamily.
CC {ECO:0000305}.
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DR EMBL; AY344494; AAQ23066.1; -; mRNA.
DR EMBL; AP004671; BAC79969.1; -; Genomic_DNA.
DR EMBL; AP004671; BAC79970.1; -; Genomic_DNA.
DR EMBL; AP005292; BAD31268.1; -; Genomic_DNA.
DR EMBL; AP005292; BAD31269.1; -; Genomic_DNA.
DR EMBL; AP008213; BAF22338.1; -; Genomic_DNA.
DR EMBL; AP014963; BAT02857.1; -; Genomic_DNA.
DR EMBL; AP014963; BAT02858.1; -; Genomic_DNA.
DR EMBL; AK063952; BAG88932.1; -; mRNA.
DR EMBL; AK102159; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015645691.1; XM_015790205.1. [Q7XHZ0-1]
DR AlphaFoldDB; Q7XHZ0; -.
DR SMR; Q7XHZ0; -.
DR IntAct; Q7XHZ0; 4.
DR MINT; Q7XHZ0; -.
DR STRING; 4530.OS07T0640900-02; -.
DR PaxDb; Q7XHZ0; -.
DR PRIDE; Q7XHZ0; -.
DR EnsemblPlants; Os07t0640900-01; Os07t0640900-01; Os07g0640900. [Q7XHZ0-2]
DR EnsemblPlants; Os07t0640900-02; Os07t0640900-02; Os07g0640900. [Q7XHZ0-1]
DR GeneID; 4344063; -.
DR Gramene; Os07t0640900-01; Os07t0640900-01; Os07g0640900. [Q7XHZ0-2]
DR Gramene; Os07t0640900-02; Os07t0640900-02; Os07g0640900. [Q7XHZ0-1]
DR KEGG; osa:4344063; -.
DR eggNOG; KOG0627; Eukaryota.
DR HOGENOM; CLU_030308_3_1_1; -.
DR InParanoid; Q7XHZ0; -.
DR OMA; FTMESQK; -.
DR OrthoDB; 1154048at2759; -.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR ExpressionAtlas; Q7XHZ0; baseline and differential.
DR Genevisible; Q7XHZ0; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015; PTHR10015; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
PE 1: Evidence at protein level;
KW Activator; Alternative splicing; DNA-binding; Nucleus; Phosphoprotein;
KW Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..310
FT /note="Heat stress transcription factor B-4b"
FT /id="PRO_0000350838"
FT REGION 124..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 196..225
FT /note="Hydrophobic repeat HR-A/B"
FT REGION 257..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 291..297
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT COMPBIAS 292..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 18..19
FT /note="GP -> AP (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_035450"
FT VAR_SEQ 20..131
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_035451"
FT CONFLICT 232
FT /note="T -> A (in Ref. 5; AK102159)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 310 AA; 34451 MW; 03913204F97CEA05 CRC64;
MAFLVERCGE MVVSMEMGPH GGGGAAAGKP VPAPFLTKTY QLVDDPCTDH IVSWGEDDTT
FVVWRPPEFA RDLLPNYFKH NNFSSFVRQL NTYGFRKIVA DRWEFANEFF RKGAKHLLAE
IHRRKSSQPP PPPMPHQPYH HHHHLNPFSL PPPPPAYHHH HLIQEEPATT AHCTVAGDGG
EGGDFLAALS EDNRQLRRRN SLLLSELAHM KKLYNDIIYF LQNHVAPVTT TTTTPSSTAM
AAAQHHLPAA ASCRLMELDS PDHSPPPPPP KTPATDGGDT VKLFGVSLHG RKKRAHRDDD
DGVHDQGSEV
