ID   HFB4C_ORYSJ             Reviewed;         394 AA.
AC   Q67U94; B7F8M8;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Heat stress transcription factor B-4c;
DE   AltName: Full=Heat stress transcription factor 22;
DE            Short=OsHsf-22;
GN   Name=HSFB4C; Synonyms=HSF22;
GN   OrderedLocusNames=Os09g0455200, LOC_Os09g28200; ORFNames=P0025H07.19;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RG   The rice full-length cDNA consortium;
RT   "Oryza sativa full length cDNA.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=15625403; DOI=10.1007/bf02712120;
RA   Baniwal S.K., Bharti K., Chan K.Y., Fauth M., Ganguli A., Kotak S.,
RA   Mishra S.K., Nover L., Port M., Scharf K.-D., Tripp J., Weber C.,
RA   Zielinski D., von Koskull-Doering P.;
RT   "Heat stress response in plants: a complex game with chaperones and more
RT   than twenty heat stress transcription factors.";
RL   J. Biosci. 29:471-487(2004).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18407058; DOI=10.1016/s1673-8527(08)60016-8;
RA   Guo J., Wu J., Ji Q., Wang C., Luo L., Yuan Y., Wang Y., Wang J.;
RT   "Genome-wide analysis of heat shock transcription factor families in rice
RT   and Arabidopsis.";
RL   J. Genet. Genomics 35:105-118(2008).
CC   -!- FUNCTION: Transcriptional regulator that specifically binds DNA of heat
CC       shock promoter elements (HSE). {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
CC   -!- DOMAIN: The hydrophobic-rich region (HR-A/B) corresponds to the
CC       oligomerization domain.
CC   -!- PTM: Exhibits temperature-dependent phosphorylation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HSF family. Class B subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AP005655; BAD38277.1; -; Genomic_DNA.
DR   EMBL; AP008215; BAF25270.1; -; Genomic_DNA.
DR   EMBL; AP014965; BAT08422.1; -; Genomic_DNA.
DR   EMBL; AK241190; BAH00976.1; -; mRNA.
DR   RefSeq; XP_015611002.1; XM_015755516.1.
DR   AlphaFoldDB; Q67U94; -.
DR   SMR; Q67U94; -.
DR   IntAct; Q67U94; 1.
DR   MINT; Q67U94; -.
DR   STRING; 4530.OS09T0455200-01; -.
DR   PaxDb; Q67U94; -.
DR   PRIDE; Q67U94; -.
DR   EnsemblPlants; Os09t0455200-01; Os09t0455200-01; Os09g0455200.
DR   GeneID; 4347251; -.
DR   Gramene; Os09t0455200-01; Os09t0455200-01; Os09g0455200.
DR   KEGG; osa:4347251; -.
DR   eggNOG; KOG0627; Eukaryota.
DR   HOGENOM; CLU_030308_3_1_1; -.
DR   InParanoid; Q67U94; -.
DR   OMA; HWREPHA; -.
DR   OrthoDB; 1154048at2759; -.
DR   Proteomes; UP000000763; Chromosome 9.
DR   Proteomes; UP000059680; Chromosome 9.
DR   Genevisible; Q67U94; OS.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000232; HSF_DNA-bd.
DR   InterPro; IPR027725; HSF_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10015; PTHR10015; 2.
DR   Pfam; PF00447; HSF_DNA-bind; 1.
DR   PRINTS; PR00056; HSFDOMAIN.
DR   SMART; SM00415; HSF; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00434; HSF_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; DNA-binding; Nucleus; Phosphoprotein; Reference proteome;
KW   Stress response; Transcription; Transcription regulation.
FT   CHAIN           1..394
FT                   /note="Heat stress transcription factor B-4c"
FT                   /id="PRO_0000350839"
FT   REGION          219..248
FT                   /note="Hydrophobic repeat HR-A/B"
FT   REGION          276..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           269..271
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   MOTIF           365..372
FT                   /note="Nuclear export signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        277..299
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..394
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   394 AA;  42036 MW;  285EB08B8EAA847A CRC64;
     MERCGSWSDC EAAAAAAQKA VPAPFLTKTY QLVDDPATDH IVSWGDDRVS TFVVWRPPEF
     ARDILPNYFK HNNFSSFVRQ LNTYGFRKVV PERWEFANEF FRKGEKQLLT EIHRRKTSSA
     STASPSPPPF FAPPHFPLFH HPGVAAAQHH HAFVGDDGVV AAHGIGMPFP QPHWREPNLP
     VATRLLALGG PAPSPSSAEA GGAGRAATAA VLMEENERLR RSNTALLQEL AHMRKLYNDI
     IYFVQNHVRP VAPSPAAAAF LQGLGMQARK KPAAANVLNN SGGSTTSSSS LTIAEEPSPP
     PQQQHLAGEK SGGEAGNSSA ARSSAPTKLF GVHLSAAPCG AGSKRASSPE EHPPTSPATK
     PRLVLECDDL SLTVAPSSSS QQQLSAASSP TSTS