ID   HFLC_BUCAI              Reviewed;         310 AA.
AC   P57630;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Protein HflC;
GN   Name=hflC; OrderedLocusNames=BU567;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: HflC and HflK could regulate a protease. {ECO:0000250}.
CC   -!- SUBUNIT: HflC and HflK may interact to form a multimeric complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family. HflC subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BA000003; BAB13257.1; -; Genomic_DNA.
DR   RefSeq; NP_240371.1; NC_002528.1.
DR   RefSeq; WP_010896164.1; NC_002528.1.
DR   AlphaFoldDB; P57630; -.
DR   SMR; P57630; -.
DR   STRING; 107806.10039223; -.
DR   MEROPS; I87.001; -.
DR   PRIDE; P57630; -.
DR   EnsemblBacteria; BAB13257; BAB13257; BAB13257.
DR   KEGG; buc:BU567; -.
DR   PATRIC; fig|107806.10.peg.570; -.
DR   eggNOG; COG0330; Bacteria.
DR   HOGENOM; CLU_059167_3_0_6; -.
DR   OMA; DFFAFYR; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0052547; P:regulation of peptidase activity; IEA:InterPro.
DR   CDD; cd03405; SPFH_HflC; 1.
DR   Gene3D; 3.30.479.30; -; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR010200; HflC.
DR   PANTHER; PTHR42911; PTHR42911; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   PIRSF; PIRSF005651; HflC; 1.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; SSF117892; 1.
DR   TIGRFAMs; TIGR01932; hflC; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..310
FT                   /note="Protein HflC"
FT                   /id="PRO_0000094070"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   310 AA;  35811 MW;  CA5095FF9F53324C CRC64;
     MNKILIFASS VLFLILSSSF FIVKEGERGI VLQFGKVLRN NELKTVVYNP GLHFKWPFLE
     TVKMLDARIH TMDNQADRFV TKEKKDLIVD SYIKWRINDF SRYYLATGGG DVFQAEVLLK
     RKFSDRLRSE IGRLNVKEIV TDSRGRLTTD VLNSLNKGSM NLEKSSLINV NSMNALGIHV
     VDVRIKQINL PVEVSDAIYN RMRAEREAVA RSQRSQGQEK AEKLRASADY KVSIILSEAR
     KEALIIKGQG EAEVTKLFAK NFNKEPDFYF FIRSLRAYEN SFKNNRNIML IDSDSQFFRY
     IKNMINIKNL