ID   ANM7_ORYSI              Reviewed;         720 AA.
AC   A2Y8B9; B8B1M3;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-JUL-2010, sequence version 3.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Protein arginine N-methyltransferase 7;
DE            EC=2.1.1.-;
GN   Name=PRMT7; ORFNames=OsI_020562, OsI_21299;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Arginine methyltransferase that can both catalyze the
CC       formation of omega-N monomethylarginine (MMA) and symmetrical
CC       dimethylarginine (sDMA). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. Protein arginine N-methyltransferase family. PRMT7
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01015}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EEC79835.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CM000131; EEC79835.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; A2Y8B9; -.
DR   SMR; A2Y8B9; -.
DR   STRING; 39946.A2Y8B9; -.
DR   Proteomes; UP000007015; Chromosome 6.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0018216; P:peptidyl-arginine methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 2.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR014644; MeTrfase_PRMT7.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR11006; PTHR11006; 1.
DR   PIRSF; PIRSF036946; Arg_N-mtase; 1.
DR   SUPFAM; SSF53335; SSF53335; 2.
DR   PROSITE; PS51678; SAM_MT_PRMT; 2.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; Repeat; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..720
FT                   /note="Protein arginine N-methyltransferase 7"
FT                   /id="PRO_0000294002"
FT   DOMAIN          54..385
FT                   /note="SAM-dependent MTase PRMT-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01015"
FT   DOMAIN          387..720
FT                   /note="SAM-dependent MTase PRMT-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01015"
FT   ACT_SITE        180
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        189
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   720 AA;  80504 MW;  6D6B83226745631B CRC64;
     MPSCCCLLGL GFPSPPSALR ILRRRMASRA FQLRLNPLTG DSEWLVVEEE EEEDHHPTPP
     PKQLLATTSY LDMLNDSARN RAYRRAIEAA VTDPSSRVLD IGAGTGLLSM MAARALAAVG
     GETRGGSVSA CESYLPMGKL MRRVLRANGM ENRVKVFHKR SDELKVGDDL DSPADILVSE
     ILDSELLGEG LIPTLQQAYD MLLAKNPKIV PYRATTYGQL VESTFLWKLH DLHNNEANAA
     DGVWLTPGEM ERIVSVKPQQ HAMQCDALED EIRLLSEPFK VFEFDFWKRP DSHREANIKI
     QTTRDGYVHA IISWWVLQLD SAGSIFYSTA PRWARQSSSE GPQRDMKDWC DHWKQCVWFM
     QGKGIPATED QVLSLRARHN QTSISYQLNI NDEACDRSSK GDHLTLLPER IALYGDKDWR
     SALINTIKNA LTVKSSPTCV VADDSMFLAL LISSMSPTSK VIAMYPGLRD KGAAYLRSVA
     DANNFSIDQI QVIGKRASSI TADDLKHKKV NLLVGEPFYL GSEGMLPWQN LRFWSVRTLL
     DSMLSEDAFI MPCKGILKLC AMSLPDLWRS RSSLKDVEGF DHSVVNETLG ACGYLPGDQQ
     GPCLPYYVWQ CGYTKKLSKV YSLMDFNFSE PIHSCFGKTK IEFSHDGTCH GFAVWIDWVL
     DERKSVVLTT GPDNRYWKQG VQLFGKPVEV NPGKSVMHVE ASFDPSTGEI TFSSSSTTCS