ID   ANM7_ORYSJ              Reviewed;         720 AA.
AC   Q5VS72; A0A0P0WRB2; A3B7K6; B9FR35;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Protein arginine N-methyltransferase 7;
DE            EC=2.1.1.-;
GN   Name=PRMT7; OrderedLocusNames=Os06g0105500, LOC_Os06g01640;
GN   ORFNames=OsJ_019028, OsJ_19828, P0644B06.25;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- FUNCTION: Arginine methyltransferase that can both catalyze the
CC       formation of omega-N monomethylarginine (MMA) and symmetrical
CC       dimethylarginine (sDMA). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. Protein arginine N-methyltransferase family. PRMT7
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU01015}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AK099594; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=EEE64946.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP001129; BAD67703.1; -; Genomic_DNA.
DR   EMBL; AP008212; BAF18470.1; -; Genomic_DNA.
DR   EMBL; AP014962; BAS95742.1; -; Genomic_DNA.
DR   EMBL; CM000143; EEE64946.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AK099594; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015641005.1; XM_015785519.1.
DR   AlphaFoldDB; Q5VS72; -.
DR   SMR; Q5VS72; -.
DR   STRING; 4530.OS06T0105500-01; -.
DR   PaxDb; Q5VS72; -.
DR   PRIDE; Q5VS72; -.
DR   EnsemblPlants; Os06t0105500-01; Os06t0105500-01; Os06g0105500.
DR   GeneID; 4339860; -.
DR   Gramene; Os06t0105500-01; Os06t0105500-01; Os06g0105500.
DR   KEGG; osa:4339860; -.
DR   eggNOG; KOG1501; Eukaryota.
DR   HOGENOM; CLU_015180_1_0_1; -.
DR   InParanoid; Q5VS72; -.
DR   OMA; LPMANCA; -.
DR   OrthoDB; 408622at2759; -.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000007752; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   Genevisible; Q5VS72; OS.
DR   GO; GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IBA:GO_Central.
DR   GO; GO:0018216; P:peptidyl-arginine methylation; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 2.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR014644; MeTrfase_PRMT7.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR11006; PTHR11006; 1.
DR   PIRSF; PIRSF036946; Arg_N-mtase; 1.
DR   SUPFAM; SSF53335; SSF53335; 2.
DR   PROSITE; PS51678; SAM_MT_PRMT; 2.
PE   2: Evidence at transcript level;
KW   Methyltransferase; Reference proteome; Repeat; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..720
FT                   /note="Protein arginine N-methyltransferase 7"
FT                   /id="PRO_0000294003"
FT   DOMAIN          54..385
FT                   /note="SAM-dependent MTase PRMT-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01015"
FT   DOMAIN          387..720
FT                   /note="SAM-dependent MTase PRMT-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01015"
FT   ACT_SITE        180
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        189
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   720 AA;  80601 MW;  03D23A2199B68B88 CRC64;
     MPSCCCLLGL GFPSPPSALR ILRRRMASRA FQLRLNPLTG DSEWLVVEEE EEEDHHPTPP
     PKQLLATTSY LDMLNDSARN RAYRRAIEAA VTDPSSRVLD IGAGTGLLSM MAARALAAVG
     GETRGGSVSA CESYLPMGKL MRRVLRANGM ENRVKVFHKR SDELKVRDDL DSPADILVSE
     ILDSELLGEG LIPTLQQAYD MLLAKNPKIV PYRATTYGQL VESTFLWKLH DLHNNEANAA
     DGVWLTPGEM ERIVSVKPQQ HAMQCDALED EIRLLSEPFK VFEFDFWKRP DSHREANIKI
     RTTRDGYVHA IISWWVLQLD SAGSIFYSTA PRWARQSSSE GPQRDMKDWC DHWKQCVWFM
     QGKGIPATED QVLSLRARHN QTSISYQLNI NDEACDRSSK GDHLTLLPER IALYGDKDWR
     SALINTIKNA LTVKSSPTCV VADDSMFLAL LISSMSPTSK VIAMYPGLRD KGAAYLRSVA
     DANNFSIDQI QVIGKRASSI TADDLKHKKV NLLVGEPFYL GSEGMLPWQN LRFWSVRTLL
     DSMLSEDAFI MPCKGILKLC AMSLPDLWRS RSSLKDVEGF DHSVVNETLG ACGCLPGDQQ
     GPCLPYYVWQ CGYTKKLSKV YSLMDFNFSE PIHSCFGKTK IEFSHDGTCH GFAVWIDWVL
     DERKSVVLTT GPDNRYWKQG VQLFSKPVEV NPGKSVMHVE ASFDPSTGEI TFSSSSTTCS