ID   HFLK_BORBU              Reviewed;         311 AA.
AC   O51221;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Protein HflK;
GN   Name=hflK; OrderedLocusNames=BB_0203;
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA   Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA   Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA   van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA   Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA   Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA   Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
CC   -!- FUNCTION: HflC and HflK could encode or regulate a protease.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: HflC and HflK may interact to form a multimeric complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family. HflK subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000783; AAC66586.1; -; Genomic_DNA.
DR   PIR; C70125; C70125.
DR   RefSeq; NP_212337.1; NC_001318.1.
DR   RefSeq; WP_002556800.1; NC_001318.1.
DR   AlphaFoldDB; O51221; -.
DR   STRING; 224326.BB_0203; -.
DR   PRIDE; O51221; -.
DR   EnsemblBacteria; AAC66586; AAC66586; BB_0203.
DR   KEGG; bbu:BB_0203; -.
DR   PATRIC; fig|224326.49.peg.600; -.
DR   HOGENOM; CLU_039173_0_1_12; -.
DR   OMA; WNEPGGN; -.
DR   Proteomes; UP000001807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd03404; SPFH_HflK; 1.
DR   Gene3D; 3.30.479.30; -; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR010201; HflK.
DR   PANTHER; PTHR43327:SF2; PTHR43327:SF2; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; SSF117892; 1.
DR   TIGRFAMs; TIGR01933; hflK; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..311
FT                   /note="Protein HflK"
FT                   /id="PRO_0000094081"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   311 AA;  35825 MW;  613BA21169D64BC2 CRC64;
     MFDIKQIFNK TYEYLIIIIT LILISIIVIA NIFIVGPSEE AIVLRLGKLN RTLDSGIHVK
     IPLIEEKFIV PVKIVQEIKF GFLISPSDIR ENDNANDESR IITGDLNIIN IEWLVQYKIR
     DPYSFKFKVE DPETTIKDIA KSSMNRLIGD NTIFEIINDN RVGITEGVKS SMNEIIDNYN
     LGIDVVQVQI RNALPPKGKV YEAFEDVNIA IQDKNKYINE GRKEFNQIVP KIKGEALKVI
     EEARGYKESR INNALADTEI FNAILDAYLK NPDITKERLY NETMKEILEN KDNIELIDKN
     FKNFLPFKEV K