ID   HFLK_BUCAI              Reviewed;         406 AA.
AC   P57631;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Protein HflK;
GN   Name=hflK; OrderedLocusNames=BU568;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: HflC and HflK could encode or regulate a protease.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: HflC and HflK may interact to form a multimeric complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family. HflK subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BA000003; BAB13258.1; -; Genomic_DNA.
DR   RefSeq; NP_240372.1; NC_002528.1.
DR   RefSeq; WP_010896165.1; NC_002528.1.
DR   AlphaFoldDB; P57631; -.
DR   SMR; P57631; -.
DR   STRING; 107806.10039224; -.
DR   EnsemblBacteria; BAB13258; BAB13258; BAB13258.
DR   KEGG; buc:BU568; -.
DR   PATRIC; fig|107806.10.peg.571; -.
DR   eggNOG; COG0330; Bacteria.
DR   HOGENOM; CLU_039173_1_1_6; -.
DR   OMA; WIVQYRI; -.
DR   Proteomes; UP000001806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd03404; SPFH_HflK; 1.
DR   Gene3D; 3.30.479.30; -; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR010201; HflK.
DR   PANTHER; PTHR43327:SF2; PTHR43327:SF2; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; SSF117892; 1.
DR   TIGRFAMs; TIGR01933; hflK; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..406
FT                   /note="Protein HflK"
FT                   /id="PRO_0000094082"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..29
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   406 AA;  46929 MW;  70BA5DD72E537DB2 CRC64;
     MVWNKPNNNK PDFDPWGNKD SKSKNCSDNK HEKKTTVLDI KNFLYNLKNI ITKKTDSSNS
     SKKITYPFSI IIFISFFIWG VSGFYTITEA ERGVVTSFGK FSHLVQPGLN WRPVFFNEVK
     PVNVETVREL ATSGIMLTAD ENVVRVEMNV QYKITNPADY LFSVCYPDDS LRQATDSALR
     GVIGHSTMDR VLTEGRTLVR SDTQKEIENT IKPYKMGITI LDVNFQTARP PEEVKAAFDD
     AIAARENREQ YVREAEAYSN EVKPKANGKA QRILEEAKSY SSRIILQAQG EVARFSKILP
     EYRIAKKITL KRLYIESMER LLRKNKKIFI DTNNNPMFFF SLDNFFSKIK IPNKNFKDHI
     KINKNHSPFN KKVKNTNYFP FLSPDNISEQ RRINSIRSDL KKIGRE