ID   HFLK_BUCAP              Reviewed;         411 AA.
AC   Q8K914;
DT   08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Protein HflK;
GN   Name=hflK; OrderedLocusNames=BUsg_548;
OS   Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=198804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sg;
RX   PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- FUNCTION: HflC and HflK could encode or regulate a protease.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: HflC and HflK may interact to form a multimeric complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family. HflK subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE013218; AAM68087.1; -; Genomic_DNA.
DR   RefSeq; WP_011054053.1; NC_004061.1.
DR   AlphaFoldDB; Q8K914; -.
DR   SMR; Q8K914; -.
DR   STRING; 198804.BUsg_548; -.
DR   EnsemblBacteria; AAM68087; AAM68087; BUsg_548.
DR   KEGG; bas:BUsg_548; -.
DR   eggNOG; COG0330; Bacteria.
DR   HOGENOM; CLU_039173_1_1_6; -.
DR   OMA; HIRESSI; -.
DR   OrthoDB; 577287at2; -.
DR   Proteomes; UP000000416; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd03404; SPFH_HflK; 1.
DR   Gene3D; 3.30.479.30; -; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR010201; HflK.
DR   InterPro; IPR001972; Stomatin_HflK_HflKC_fam.
DR   PANTHER; PTHR43327:SF2; PTHR43327:SF2; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   PRINTS; PR00721; STOMATIN.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; SSF117892; 1.
DR   TIGRFAMs; TIGR01933; hflK; 1.
PE   3: Inferred from homology;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..411
FT                   /note="Protein HflK"
FT                   /id="PRO_0000094083"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..34
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   411 AA;  47797 MW;  1B22CF10DA8BE779 CRC64;
     MAWNKFNNSE PELDPWGKKN SQEKNGSKNK DDRKNHEKII TLDFKKFLYN INNIFNKTNN
     SQNLSKNKIN PFLIIAFVSF FVWCFSGFYT IKEAERGVVT TFGKFSHLVA PGLNWRPVFI
     NEVKAVNVET VRELATSGVM LTSDENVVRV EMNVQYKITD PADYLFSVAY PDDSLRQATD
     SALRGVIGHS NMDRVLTEGR TLIRSDTQKE IEETIKPYKL GITILDVNFQ TARPPEEVKE
     AFDDAIAARE NREQYIREAE AYSNEVQPKA HGKAQRILEE AKAYSSRRIL EAQGEVVRFL
     KILPEYRKNK EMTLKRLYIE SMEKLLSKTK KIFIDKKNHS KLFLSLNNFF HQDKFNKQDL
     FNNPINLSKN HSCSFQKNKE INDVSSLPPS DFFKKRRIES IRTNIKNIER E