ID   HFLK_BUCBP              Reviewed;         417 AA.
AC   Q89A39;
DT   14-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Protein HflK;
GN   Name=hflK; OrderedLocusNames=bbp_513;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- FUNCTION: HflC and HflK could encode or regulate a protease.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: HflC and HflK may interact to form a multimeric complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the band 7/mec-2 family. HflK subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE016826; AAO27216.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q89A39; -.
DR   SMR; Q89A39; -.
DR   STRING; 224915.bbp_513; -.
DR   EnsemblBacteria; AAO27216; AAO27216; bbp_513.
DR   KEGG; bab:bbp_513; -.
DR   eggNOG; COG0330; Bacteria.
DR   HOGENOM; CLU_039173_1_1_6; -.
DR   OMA; WNEPGGN; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd03404; SPFH_HflK; 1.
DR   Gene3D; 3.30.479.30; -; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   InterPro; IPR010201; HflK.
DR   PANTHER; PTHR43327:SF2; PTHR43327:SF2; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; SSF117892; 1.
DR   TIGRFAMs; TIGR01933; hflK; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..417
FT                   /note="Protein HflK"
FT                   /id="PRO_0000094084"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   417 AA;  48545 MW;  DD4C2F0B10265E31 CRC64;
     MEKNMAWNEP SDSEKDKDPW NKKDKKLKNF DENKKSKLYL FLEIECLVNF LKRKKKIFFS
     ESGSFKYFKN LITMIIFTTI IFLIGSGFYF IQESEYGVVT CFGKFSYLAN PGLHWKPILI
     QKVIPIDVST VREINTSGTI LTYSEHFVQV NMTVQYRIVD PKKYLFSVTN PDNCLRQSIN
     SALRSVISRS NIDIFLKNEF SLLAKNDIKV NIQKIIKPYH MGIVISDINF RTLYLPQAVK
     LAFEDIFSAI ESKKQSLNEA RIYSNEIKSQ AFYNAKKILI EAKSDRLRTI LNAQGIIFKF
     LKILPIYKSS KKITTIQLYF DCMEKIFSHT RKVLTNSDNN FFLFSLNDLF LKNNYNSLTQ
     SHSNSNKHSS MLNTVSSSHV KSIDHVNSNN LLISSNNIIN QRKLNSFRKD YLRIGRE