ID   HFOB_METFO              Reviewed;          67 AA.
AC   P48784;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Archaeal histone B;
GN   Name=hfoB;
OS   Methanobacterium formicicum.
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX   NCBI_TaxID=2162;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBUNIT.
RC   STRAIN=JF-1;
RX   PubMed=7836329; DOI=10.1128/jb.177.3.858-860.1995;
RA   Darcy T.J., Sandman K.M., Reeve J.N.;
RT   "Methanobacterium formicicum, a mesophilic methanogen, contains three HFo
RT   histones.";
RL   J. Bacteriol. 177:858-860(1995).
CC   -!- FUNCTION: Binds and compact DNA (95 to 150 base pairs) to form
CC       nucleosome-like structures that contain positive DNA supercoils.
CC       Increases the resistance of DNA to thermal denaturation (in vitro).
CC       {ECO:0000305|PubMed:7836329}.
CC   -!- SUBUNIT: Homodimer or heterodimer with another histone
CC       (PubMed:7836329). Dimers then assemble into higher oligomers, with the
CC       DNA wrapped around the protein core (By similarity).
CC       {ECO:0000250|UniProtKB:P19267, ECO:0000305|PubMed:7836329}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Chromosome
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the archaeal histone HMF family. {ECO:0000305}.
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DR   EMBL; U12929; AAA67720.1; -; Genomic_DNA.
DR   RefSeq; WP_004031090.1; NZ_CP017767.1.
DR   AlphaFoldDB; P48784; -.
DR   SMR; P48784; -.
DR   STRING; 2162.BRM9_0598; -.
DR   GeneID; 35125999; -.
DR   OrthoDB; 127272at2157; -.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR003958; CBFA_NFYB_domain.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR   Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR   SMART; SM00803; TAF; 1.
DR   SUPFAM; SSF47113; SSF47113; 1.
PE   1: Evidence at protein level;
KW   Chromosome; Cytoplasm; DNA-binding.
FT   CHAIN           1..67
FT                   /note="Archaeal histone B"
FT                   /id="PRO_0000154986"
FT   REGION          19..21
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250|UniProtKB:P19267"
FT   REGION          53..56
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250|UniProtKB:P19267"
FT   SITE            13
FT                   /note="Interaction with DNA"
FT                   /evidence="ECO:0000250|UniProtKB:P19267"
SQ   SEQUENCE   67 AA;  7149 MW;  1132F83ACAD88445 CRC64;
     MELPIAPIGR IIKNAGAERV SDDAREALAK ALEEKGETIA TEAVKLAKHA GRKTVKASDV
     ELAVKRL