ID   HFQ_BACMK               Reviewed;          74 AA.
AC   A9VR02;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=RNA-binding protein Hfq {ECO:0000255|HAMAP-Rule:MF_00436};
GN   Name=hfq {ECO:0000255|HAMAP-Rule:MF_00436};
GN   OrderedLocusNames=BcerKBAB4_3478;
OS   Bacillus mycoides (strain KBAB4) (Bacillus weihenstephanensis).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=315730;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KBAB4;
RX   PubMed=17434157; DOI=10.1016/j.cbi.2007.03.003;
RA   Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C.,
RA   Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V.,
RA   Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "Extending the Bacillus cereus group genomics to putative food-borne
RT   pathogens of different toxicity.";
RL   Chem. Biol. Interact. 171:236-249(2008).
CC   -!- FUNCTION: RNA chaperone that binds small regulatory RNA (sRNAs) and
CC       mRNAs to facilitate mRNA translational regulation in response to
CC       envelope stress, environmental stress and changes in metabolite
CC       concentrations. Also binds with high specificity to tRNAs.
CC       {ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SIMILARITY: Belongs to the Hfq family. {ECO:0000255|HAMAP-
CC       Rule:MF_00436}.
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DR   EMBL; CP000903; ABY44651.1; -; Genomic_DNA.
DR   RefSeq; WP_000813896.1; NC_010184.1.
DR   AlphaFoldDB; A9VR02; -.
DR   SMR; A9VR02; -.
DR   STRING; 315730.BcerKBAB4_3478; -.
DR   EnsemblBacteria; ABY44651; ABY44651; BcerKBAB4_3478.
DR   GeneID; 59155794; -.
DR   GeneID; 64199047; -.
DR   GeneID; 67508350; -.
DR   KEGG; bwe:BcerKBAB4_3478; -.
DR   eggNOG; COG1923; Bacteria.
DR   HOGENOM; CLU_113688_3_0_9; -.
DR   OMA; QQMVYKH; -.
DR   Proteomes; UP000002154; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01716; Hfq; 1.
DR   HAMAP; MF_00436; Hfq; 1.
DR   InterPro; IPR005001; Hfq.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   PANTHER; PTHR34772; PTHR34772; 1.
DR   Pfam; PF17209; Hfq; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   TIGRFAMs; TIGR02383; Hfq; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Stress response.
FT   CHAIN           1..74
FT                   /note="RNA-binding protein Hfq"
FT                   /id="PRO_1000190306"
SQ   SEQUENCE   74 AA;  8646 MW;  621400020EF87C50 CRC64;
     MKQSINIQDQ FLNQLRKENT FVTLYLLNGF QLRGLIKGFD NFTVLLETEG KQQLIYKHAI
     STFVPQKNVS IELE