ID   HFQ_CLOBJ               Reviewed;          85 AA.
AC   C1FNT6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=RNA-binding protein Hfq {ECO:0000255|HAMAP-Rule:MF_00436};
GN   Name=hfq {ECO:0000255|HAMAP-Rule:MF_00436}; OrderedLocusNames=CLM_1954;
OS   Clostridium botulinum (strain Kyoto / Type A2).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=536232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Kyoto / Type A2;
RA   Shrivastava S., Brinkac L.M., Brown J.L., Bruce D., Detter C.C.,
RA   Johnson E.A., Munk C.A., Smith L.A., Smith T.J., Sutton G., Brettin T.S.;
RT   "Genome sequence of Clostridium botulinum A2 Kyoto.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: RNA chaperone that binds small regulatory RNA (sRNAs) and
CC       mRNAs to facilitate mRNA translational regulation in response to
CC       envelope stress, environmental stress and changes in metabolite
CC       concentrations. Also binds with high specificity to tRNAs.
CC       {ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SIMILARITY: Belongs to the Hfq family. {ECO:0000255|HAMAP-
CC       Rule:MF_00436}.
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DR   EMBL; CP001581; ACO83972.1; -; Genomic_DNA.
DR   RefSeq; WP_003358923.1; NC_012563.1.
DR   AlphaFoldDB; C1FNT6; -.
DR   SMR; C1FNT6; -.
DR   STRING; 536232.CLM_1954; -.
DR   EnsemblBacteria; ACO83972; ACO83972; CLM_1954.
DR   GeneID; 5186052; -.
DR   KEGG; cby:CLM_1954; -.
DR   eggNOG; COG1923; Bacteria.
DR   HOGENOM; CLU_113688_0_2_9; -.
DR   OMA; QQMVYKH; -.
DR   Proteomes; UP000001374; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01716; Hfq; 1.
DR   HAMAP; MF_00436; Hfq; 1.
DR   InterPro; IPR005001; Hfq.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   PANTHER; PTHR34772; PTHR34772; 1.
DR   Pfam; PF17209; Hfq; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   TIGRFAMs; TIGR02383; Hfq; 1.
PE   3: Inferred from homology;
KW   RNA-binding; Stress response.
FT   CHAIN           1..85
FT                   /note="RNA-binding protein Hfq"
FT                   /id="PRO_1000135026"
SQ   SEQUENCE   85 AA;  9664 MW;  CA85DE139548AE1A CRC64;
     MTKVVNNLQD IFLNGARKNR IPVTIYLTNG FQLKGFVKGF DNFTVILDSD GKQMMIYKHA
     ISTINPAKPL LFVQNPNGDD YKDKE