ID   HFQ_PSEA7               Reviewed;          82 AA.
AC   A6VD57;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=RNA-binding protein Hfq {ECO:0000255|HAMAP-Rule:MF_00436};
GN   Name=hfq {ECO:0000255|HAMAP-Rule:MF_00436}; OrderedLocusNames=PSPA7_5673;
OS   Pseudomonas aeruginosa (strain PA7).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=381754;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PA7;
RA   Dodson R.J., Harkins D., Paulsen I.T.;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: RNA chaperone that binds small regulatory RNA (sRNAs) and
CC       mRNAs to facilitate mRNA translational regulation in response to
CC       envelope stress, environmental stress and changes in metabolite
CC       concentrations. Also binds with high specificity to tRNAs.
CC       {ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SIMILARITY: Belongs to the Hfq family. {ECO:0000255|HAMAP-
CC       Rule:MF_00436}.
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DR   EMBL; CP000744; ABR82556.1; -; Genomic_DNA.
DR   RefSeq; WP_003095657.1; NC_009656.1.
DR   PDB; 5I21; X-ray; 1.55 A; A/B/C=1-82.
DR   PDBsum; 5I21; -.
DR   AlphaFoldDB; A6VD57; -.
DR   SMR; A6VD57; -.
DR   EnsemblBacteria; ABR82556; ABR82556; PSPA7_5673.
DR   KEGG; pap:PSPA7_5673; -.
DR   HOGENOM; CLU_113688_2_2_6; -.
DR   OMA; QQMVYKH; -.
DR   OrthoDB; 1989988at2; -.
DR   Proteomes; UP000001582; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01716; Hfq; 1.
DR   HAMAP; MF_00436; Hfq; 1.
DR   InterPro; IPR005001; Hfq.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   PANTHER; PTHR34772; PTHR34772; 1.
DR   Pfam; PF17209; Hfq; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   TIGRFAMs; TIGR02383; Hfq; 1.
PE   1: Evidence at protein level;
KW   3D-structure; RNA-binding; Stress response.
FT   CHAIN           1..82
FT                   /note="RNA-binding protein Hfq"
FT                   /id="PRO_1000025924"
FT   HELIX           8..17
FT                   /evidence="ECO:0007829|PDB:5I21"
FT   STRAND          21..26
FT                   /evidence="ECO:0007829|PDB:5I21"
FT   STRAND          31..39
FT                   /evidence="ECO:0007829|PDB:5I21"
FT   STRAND          41..55
FT                   /evidence="ECO:0007829|PDB:5I21"
FT   HELIX           56..58
FT                   /evidence="ECO:0007829|PDB:5I21"
FT   STRAND          59..66
FT                   /evidence="ECO:0007829|PDB:5I21"
SQ   SEQUENCE   82 AA;  9104 MW;  1153661DC4C5AE2F CRC64;
     MSKGHSLQDP YLNTLRKERV PVSIYLVNGI KLQGQIESFD QFVILLKNTV SQMVYKHAIS
     TVVPSRPVRL PSGDQPAEPG NA