ID   HFQ_PSEAI               Reviewed;          82 AA.
AC   B3EWP0;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   25-MAY-2022, entry version 24.
DE   RecName: Full=RNA-binding protein Hfq {ECO:0000255|HAMAP-Rule:MF_00436};
GN   Name=hfq {ECO:0000255|HAMAP-Rule:MF_00436};
OS   Pseudomonas aeruginosa.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=287;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE.
RC   STRAIN=DSGPM4;
RA   Diptendu S., Goutam P.;
RL   Submitted (MAY-2012) to UniProtKB.
CC   -!- FUNCTION: RNA chaperone that binds small regulatory RNA (sRNAs) and
CC       mRNAs to facilitate mRNA translational regulation in response to
CC       envelope stress, environmental stress and changes in metabolite
CC       concentrations. Also binds with high specificity to tRNAs.
CC       {ECO:0000250|UniProtKB:P0A6X3, ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000250|UniProtKB:P0A6X3, ECO:0000255|HAMAP-
CC       Rule:MF_00436}.
CC   -!- SIMILARITY: Belongs to the Hfq family. {ECO:0000255|HAMAP-
CC       Rule:MF_00436}.
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DR   AlphaFoldDB; B3EWP0; -.
DR   SMR; B3EWP0; -.
DR   eggNOG; COG1923; Bacteria.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01716; Hfq; 1.
DR   HAMAP; MF_00436; Hfq; 1.
DR   InterPro; IPR005001; Hfq.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   PANTHER; PTHR34772; PTHR34772; 1.
DR   Pfam; PF17209; Hfq; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   TIGRFAMs; TIGR02383; Hfq; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; RNA-binding; Stress response.
FT   CHAIN           1..82
FT                   /note="RNA-binding protein Hfq"
FT                   /id="PRO_0000419337"
SQ   SEQUENCE   82 AA;  9067 MW;  114EA7C1C4C5AE2F CRC64;
     MSKGHSLQDP YLNTLRKERV PVSIYLVNGI KLQGQIESFD QFVILLKNTV SQMVYKTAIS
     TVVPSRPVRL PSGDQPAEPG NA