HFQ_RALSO
ID HFQ_RALSO Reviewed; 79 AA.
AC Q8Y025;
DT 27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=RNA-binding protein Hfq {ECO:0000255|HAMAP-Rule:MF_00436};
GN Name=hfq {ECO:0000255|HAMAP-Rule:MF_00436}; OrderedLocusNames=RSc1220;
GN ORFNames=RS02722;
OS Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=267608;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=11823852; DOI=10.1038/415497a;
RA Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL Nature 415:497-502(2002).
CC -!- FUNCTION: RNA chaperone that binds small regulatory RNA (sRNAs) and
CC mRNAs to facilitate mRNA translational regulation in response to
CC envelope stress, environmental stress and changes in metabolite
CC concentrations. Also binds with high specificity to tRNAs.
CC {ECO:0000255|HAMAP-Rule:MF_00436}.
CC -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_00436}.
CC -!- SIMILARITY: Belongs to the Hfq family. {ECO:0000255|HAMAP-
CC Rule:MF_00436}.
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DR EMBL; AL646052; CAD14922.1; -; Genomic_DNA.
DR RefSeq; WP_003263868.1; NC_003295.1.
DR AlphaFoldDB; Q8Y025; -.
DR SMR; Q8Y025; -.
DR STRING; 267608.RSc1220; -.
DR EnsemblBacteria; CAD14922; CAD14922; RSc1220.
DR GeneID; 61526279; -.
DR KEGG; rso:RSc1220; -.
DR eggNOG; COG1923; Bacteria.
DR HOGENOM; CLU_113688_2_2_4; -.
DR OMA; QQMVYKH; -.
DR Proteomes; UP000001436; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd01716; Hfq; 1.
DR HAMAP; MF_00436; Hfq; 1.
DR InterPro; IPR005001; Hfq.
DR InterPro; IPR010920; LSM_dom_sf.
DR PANTHER; PTHR34772; PTHR34772; 1.
DR Pfam; PF17209; Hfq; 1.
DR SUPFAM; SSF50182; SSF50182; 1.
DR TIGRFAMs; TIGR02383; Hfq; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding; Stress response.
FT CHAIN 1..79
FT /note="RNA-binding protein Hfq"
FT /id="PRO_0000095660"
SQ SEQUENCE 79 AA; 8872 MW; 8C138A4742853799 CRC64;
MSNKGQLLQD PFLNALRKEH VPVSIYLVNG IKLQGNIESF DQYVVLLRNT VTQMVYKHAI
STVVPARAVN FRVDEASDA