ID   HFQ_SYNWW               Reviewed;          82 AA.
AC   Q0AYA9;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=RNA-binding protein Hfq {ECO:0000255|HAMAP-Rule:MF_00436};
GN   Name=hfq {ECO:0000255|HAMAP-Rule:MF_00436}; OrderedLocusNames=Swol_0980;
OS   Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Syntrophomonadaceae;
OC   Syntrophomonas.
OX   NCBI_TaxID=335541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2245B / Goettingen;
RX   PubMed=21966920; DOI=10.1111/j.1462-2920.2010.02237.x;
RA   Sieber J.R., Sims D.R., Han C., Kim E., Lykidis A., Lapidus A.L.,
RA   McDonnald E., Rohlin L., Culley D.E., Gunsalus R., McInerney M.J.;
RT   "The genome of Syntrophomonas wolfei: new insights into syntrophic
RT   metabolism and biohydrogen production.";
RL   Environ. Microbiol. 12:2289-2301(2010).
CC   -!- FUNCTION: RNA chaperone that binds small regulatory RNA (sRNAs) and
CC       mRNAs to facilitate mRNA translational regulation in response to
CC       envelope stress, environmental stress and changes in metabolite
CC       concentrations. Also binds with high specificity to tRNAs.
CC       {ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000255|HAMAP-Rule:MF_00436}.
CC   -!- SIMILARITY: Belongs to the Hfq family. {ECO:0000255|HAMAP-
CC       Rule:MF_00436}.
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DR   EMBL; CP000448; ABI68295.1; -; Genomic_DNA.
DR   RefSeq; WP_011640400.1; NC_008346.1.
DR   AlphaFoldDB; Q0AYA9; -.
DR   SMR; Q0AYA9; -.
DR   STRING; 335541.Swol_0980; -.
DR   EnsemblBacteria; ABI68295; ABI68295; Swol_0980.
DR   KEGG; swo:Swol_0980; -.
DR   eggNOG; COG1923; Bacteria.
DR   HOGENOM; CLU_113688_0_2_9; -.
DR   OMA; MIANHNI; -.
DR   OrthoDB; 1989988at2; -.
DR   Proteomes; UP000001968; Chromosome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01716; Hfq; 1.
DR   HAMAP; MF_00436; Hfq; 1.
DR   InterPro; IPR005001; Hfq.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   PANTHER; PTHR34772; PTHR34772; 1.
DR   Pfam; PF17209; Hfq; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   TIGRFAMs; TIGR02383; Hfq; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding; Stress response.
FT   CHAIN           1..82
FT                   /note="RNA-binding protein Hfq"
FT                   /id="PRO_0000265197"
SQ   SEQUENCE   82 AA;  9307 MW;  E6893A99EF86021C CRC64;
     MSKSQINLQD AFLNQVRKDK IPVTVFLVNG FQIKGMVRGF DNFTVIIEVD QKQQLVYKHA
     ISTVAPLRPI SMLNLEAKSD DD