ID   HGH1_DICDI              Reviewed;         355 AA.
AC   Q76NW7; Q550H8;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Protein HGH1 homolog;
GN   ORFNames=DDB_G0276861;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the HGH1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000019; EAL68932.1; -; Genomic_DNA.
DR   RefSeq; XP_642954.1; XM_637862.1.
DR   AlphaFoldDB; Q76NW7; -.
DR   SMR; Q76NW7; -.
DR   STRING; 44689.DDB0266827; -.
DR   PaxDb; Q76NW7; -.
DR   PRIDE; Q76NW7; -.
DR   EnsemblProtists; EAL68932; EAL68932; DDB_G0276861.
DR   GeneID; 8620823; -.
DR   KEGG; ddi:DDB_G0276861; -.
DR   dictyBase; DDB_G0276861; -.
DR   eggNOG; KOG2973; Eukaryota.
DR   HOGENOM; CLU_037769_3_0_1; -.
DR   InParanoid; Q76NW7; -.
DR   OMA; HRWEKDV; -.
DR   PhylomeDB; Q76NW7; -.
DR   PRO; PR:Q76NW7; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039717; Hgh1.
DR   InterPro; IPR007206; Protein_HGH1_C.
DR   InterPro; IPR007205; Protein_HGH1_N.
DR   PANTHER; PTHR13387; PTHR13387; 1.
DR   Pfam; PF04063; DUF383; 1.
DR   Pfam; PF04064; DUF384; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..355
FT                   /note="Protein HGH1 homolog"
FT                   /id="PRO_0000331585"
FT   REGION          324..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        324..347
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   355 AA;  40941 MW;  BA2A9C3ACAC9A31C CRC64;
     MDQLPELVPF LLEPKSEIKL LALQHLLGVS DNQEARDILK STQIINNCIK LITDSNHVVV
     RHALTILINL CQDTDMLNDI VKKNIVPRLV DGTTDTKNKM SEIFAMLLSN VTHTKEGCLS
     LMQCGKELEA FFIMKLVQVL TMDSNQEDYF KSTKNNWIVN IILNVTQIQE GRKIVLDKEN
     QIFKEILPLV RHENVIKRRG ILGIIRNCCY SEQHHDYLIS PEVDILTKLC LPIRGNDKLD
     DDDLVGLHID LHNSSLPIGN ERDQDRECRK MVVESLIFLT GTKKGRVSMR TAKIYPILRN
     LFNFETEEEL RDNVEKVVEL IIRDEEGDPT PEEIEQMNKK QKLEDEDAQF ETDEI