ID   HGLY_MANSE              Reviewed;         233 AA.
AC   Q25513;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=27 kDa hemolymph glycoprotein;
DE   Flags: Precursor;
OS   Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Sphingidae; Sphinginae; Sphingini; Manduca.
OX   NCBI_TaxID=7130 {ECO:0000312|EMBL:AAA74052.1};
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 34-48, TISSUE SPECIFICITY,
RP   DEVELOPMENTAL STAGE, AND GLYCOSYLATION.
RC   TISSUE=Larval fat body;
RX   PubMed=7742978; DOI=10.1111/j.1365-2583.1995.tb00002.x;
RA   Samaraweera P., Law J.H.;
RT   "Isolation, cloning and deduced amino acid sequence of a novel glycoprotein
RT   from the haemolymph of the hawkmoth Manduca sexta.";
RL   Insect Mol. Biol. 4:7-13(1995).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Hemolymph. {ECO:0000269|PubMed:7742978}.
CC   -!- DEVELOPMENTAL STAGE: Expressed during all stages of development.
CC       {ECO:0000269|PubMed:7742978}.
CC   -!- PTM: N-glycosylated. {ECO:0000269|PubMed:7742978, ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0408 family. {ECO:0000305}.
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DR   EMBL; L31964; AAA74052.1; -; mRNA.
DR   AlphaFoldDB; Q25513; -.
DR   SMR; Q25513; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009832; DUF1397.
DR   PANTHER; PTHR20997; PTHR20997; 1.
DR   Pfam; PF07165; DUF1397; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..233
FT                   /note="27 kDa hemolymph glycoprotein"
FT                   /id="PRO_0000021415"
FT   CARBOHYD        125
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        156
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   233 AA;  25941 MW;  C665966D07488C43 CRC64;
     MIWKTLIVAF MATAVLAQEI DLSDQRREQY RNMLAAQCRK MGAEDKVKDV ESSVRNFVEC
     LRGIVDPQAI KKEIEEAKPK GELDEVFKKY CAKAPVLKTC ISSLLDGVRP CVDKVAIDHY
     GPLLNTTNQL IDFVCYKDGE RIALFIAHGG SECFKNSTED LKKCAEEMKN SFPSVEAAKA
     MSLPDKCGKF DDLTTCMVTS LEKCENPTPA NMAESLLKFI RKDSPCNAAV PKD