HHO3_ARATH
ID HHO3_ARATH Reviewed; 344 AA.
AC Q9FPE8; Q8LDM3; Q9C6M4;
DT 12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 158.
DE RecName: Full=Transcription factor HHO3 {ECO:0000305};
DE AltName: Full=MYB-domain transcription factor HHO3 {ECO:0000305};
DE AltName: Full=Protein HRS1 HOMOLOG 3 {ECO:0000305};
GN Name=HHO3 {ECO:0000305};
GN OrderedLocusNames=At1g25550 {ECO:0000312|Araport:AT1G25550};
GN ORFNames=F2J7.21 {ECO:0000312|EMBL:AAG50807.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transcription factor involved in phosphate signaling
CC in roots. {ECO:0000250|UniProtKB:Q9FX67}.
CC -!- INTERACTION:
CC Q9FPE8; Q8S307: BZR1; NbExp=3; IntAct=EBI-2298866, EBI-1803261;
CC Q9FPE8; O80340: ERF4; NbExp=3; IntAct=EBI-2298866, EBI-966009;
CC Q9FPE8; Q38828: IAA10; NbExp=3; IntAct=EBI-2298866, EBI-3946434;
CC Q9FPE8; P93830: IAA17; NbExp=3; IntAct=EBI-2298866, EBI-632243;
CC Q9FPE8; Q9FNZ4: NIMIN-3; NbExp=3; IntAct=EBI-2298866, EBI-541115;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG50807.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAM63125.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC079281; AAG50807.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE30641.1; -; Genomic_DNA.
DR EMBL; AF326890; AAG41472.1; -; mRNA.
DR EMBL; AF339707; AAK00389.1; -; mRNA.
DR EMBL; AF372906; AAK49622.1; -; mRNA.
DR EMBL; BT002674; AAO11590.1; -; mRNA.
DR EMBL; AY085913; AAM63125.1; ALT_INIT; mRNA.
DR PIR; H86385; H86385.
DR RefSeq; NP_564236.1; NM_102366.4.
DR AlphaFoldDB; Q9FPE8; -.
DR SMR; Q9FPE8; -.
DR IntAct; Q9FPE8; 26.
DR STRING; 3702.AT1G25550.1; -.
DR iPTMnet; Q9FPE8; -.
DR PaxDb; Q9FPE8; -.
DR PRIDE; Q9FPE8; -.
DR ProteomicsDB; 230277; -.
DR EnsemblPlants; AT1G25550.1; AT1G25550.1; AT1G25550.
DR GeneID; 839142; -.
DR Gramene; AT1G25550.1; AT1G25550.1; AT1G25550.
DR KEGG; ath:AT1G25550; -.
DR Araport; AT1G25550; -.
DR TAIR; locus:2031210; AT1G25550.
DR eggNOG; ENOG502QSXV; Eukaryota.
DR HOGENOM; CLU_036551_0_0_1; -.
DR InParanoid; Q9FPE8; -.
DR OMA; SEHIQSE; -.
DR OrthoDB; 907731at2759; -.
DR PhylomeDB; Q9FPE8; -.
DR PRO; PR:Q9FPE8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FPE8; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:TAIR.
DR GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR GO; GO:0016036; P:cellular response to phosphate starvation; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR044787; HRS1-like.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR006447; Myb_dom_plants.
DR PANTHER; PTHR31003; PTHR31003; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..344
FT /note="Transcription factor HHO3"
FT /id="PRO_0000439546"
FT DOMAIN 206..266
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 237..262
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 90..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 306..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 309
FT /note="T -> S (in Ref. 4; AAM63125)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 344 AA; 38849 MW; A75FDDD0908FDCFB CRC64;
MMMFKSGDMD YTQKMKRCHE YVEALEEEQK KIQVFQRELP LCLELVTQAI ESCRKELSES
SEHVGGQSEC SERTTSECGG AVFEEFMPIK WSSASSDETD KDEEAEKTEM MTNENNDGDK
KKSDWLRSVQ LWNQSPDPQP NNKKPMVIEV KRSAGAFQPF QKEKPKAADS QPLIKAITPT
STTTTSSTAE TVGGGKEFEE QKQSHSNRKQ RRCWSPELHR RFLHALQQLG GSHVATPKQI
RDLMKVDGLT NDEVKSHLQK YRLHTRRPAT PVVRTGGENP QQRQFMVMEG IWVPSHDTTN
NRVYAPVATQ PPQSSTSGER SNRGCKSPAT SSTTTHTPHL LPLS
