HIBC8_ARATH
ID HIBC8_ARATH Reviewed; 387 AA.
AC Q9SHJ8; Q56XU5;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-MAR-2010, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase-like protein 5;
DE EC=3.1.2.-;
GN OrderedLocusNames=At1g06550; ORFNames=F12K11.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=11404361; DOI=10.1074/jbc.m104679200;
RA Zolman B.K., Monroe-Augustus M., Thompson B., Hawes J.W., Krukenberg K.A.,
RA Matsuda S.P., Bartel B.;
RT "chy1, an Arabidopsis mutant with impaired beta-oxidation, is defective in
RT a peroxisomal beta-hydroxyisobutyryl-CoA hydrolase.";
RL J. Biol. Chem. 276:31037-31046(2001).
RN [6]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF24814.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC007592; AAF24814.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28004.1; -; Genomic_DNA.
DR EMBL; AK221578; BAD95058.1; -; mRNA.
DR EMBL; BT022051; AAY25463.1; -; mRNA.
DR EMBL; BT026035; ABG48391.1; -; mRNA.
DR RefSeq; NP_172142.2; NM_100534.4.
DR AlphaFoldDB; Q9SHJ8; -.
DR SMR; Q9SHJ8; -.
DR STRING; 3702.AT1G06550.1; -.
DR iPTMnet; Q9SHJ8; -.
DR PaxDb; Q9SHJ8; -.
DR PRIDE; Q9SHJ8; -.
DR ProteomicsDB; 230389; -.
DR EnsemblPlants; AT1G06550.1; AT1G06550.1; AT1G06550.
DR GeneID; 837166; -.
DR Gramene; AT1G06550.1; AT1G06550.1; AT1G06550.
DR KEGG; ath:AT1G06550; -.
DR Araport; AT1G06550; -.
DR TAIR; locus:2009180; AT1G06550.
DR eggNOG; ENOG502QTE8; Eukaryota.
DR HOGENOM; CLU_009834_22_1_1; -.
DR InParanoid; Q9SHJ8; -.
DR OMA; CNHIHTY; -.
DR OrthoDB; 1369862at2759; -.
DR PhylomeDB; Q9SHJ8; -.
DR BioCyc; ARA:AT1G06550-MON; -.
DR PRO; PR:Q9SHJ8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SHJ8; baseline and differential.
DR Genevisible; Q9SHJ8; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005576; C:extracellular region; HDA:TAIR.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IBA:GO_Central.
DR GO; GO:0006574; P:valine catabolic process; IBA:GO_Central.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176; PTHR43176; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; SSF52096; 1.
PE 1: Evidence at protein level;
KW Acetylation; Hydrolase; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..387
FT /note="3-hydroxyisobutyryl-CoA hydrolase-like protein 5"
FT /id="PRO_0000392984"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0007744|PubMed:22223895"
SQ SEQUENCE 387 AA; 43257 MW; 06D868E502E71043 CRC64;
MAQEGQNIDE PVVIGEEKGS VRLTTLNRPR QLNVISPEVV FKLAEYLELW EKDDQTKLIL
IKGTGRAFSA GGDLKVFYHG QESKDSCLEV VYRMYWLCYH IHTYKKTQVS LVNGISMGGG
AALMVPMKFS VVTEKTVFAT PEASFGFHTD CGFSYIHSRL PGHLGEFLAL TGARLNGKEL
VAIGMATHFV PSGKLMDLEA RLVSLDSGDA DVVQSTIEEF SEKVNLDKDS ILNKQSVINE
CFSKESVKQI IQAFEAEASK DGNEWITPVI KGLKRSSPTG LKIVLQSIRE GRKQTLSDCL
KKEFRLTLNI LRKTISPDMY EGIRALTIDK DNSPKWNPAT LDEVDDEKIN SVFKLFEDDD
IELQIPETEE NRWGGKYETS GYASVRG
