ID   HIDE1_MOUSE             Reviewed;         222 AA.
AC   Q75VT8; Q75VT7;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Protein HIDE1;
DE   AltName: Full=Highly expressed in immature dendritic cell transcript 1 protein;
DE   Flags: Precursor;
GN   Name=Hide1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
RC   TISSUE=Spleen;
RA   Nakagawa T., Kurei S., Toji S., Nakamura A., Kishi Y., Yahara I.;
RT   "High expression genes of immature dendritic cell.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006;
RA   Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,
RA   Thibault P.;
RT   "The phagosomal proteome in interferon-gamma-activated macrophages.";
RL   Immunity 30:143-154(2009).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Spleen;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q75VT8-1; Sequence=Displayed;
CC       Name=2; Synonyms=SHIDE1;
CC         IsoId=Q75VT8-2; Sequence=VSP_034226;
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DR   EMBL; AB124611; BAD12080.1; -; mRNA.
DR   EMBL; AB124612; BAD12081.1; -; mRNA.
DR   CCDS; CCDS22905.2; -. [Q75VT8-2]
DR   CCDS; CCDS57661.1; -. [Q75VT8-1]
DR   RefSeq; NP_001185723.1; NM_001198794.1. [Q75VT8-1]
DR   RefSeq; NP_996259.2; NM_206536.2. [Q75VT8-2]
DR   AlphaFoldDB; Q75VT8; -.
DR   SMR; Q75VT8; -.
DR   BioGRID; 238213; 1.
DR   GlyGen; Q75VT8; 1 site.
DR   iPTMnet; Q75VT8; -.
DR   PhosphoSitePlus; Q75VT8; -.
DR   jPOST; Q75VT8; -.
DR   MaxQB; Q75VT8; -.
DR   PaxDb; Q75VT8; -.
DR   PeptideAtlas; Q75VT8; -.
DR   PRIDE; Q75VT8; -.
DR   Ensembl; ENSMUST00000086361; ENSMUSP00000083547; ENSMUSG00000057191. [Q75VT8-1]
DR   Ensembl; ENSMUST00000173769; ENSMUSP00000134056; ENSMUSG00000057191. [Q75VT8-2]
DR   GeneID; 382062; -.
DR   KEGG; mmu:382062; -.
DR   UCSC; uc009olt.2; mouse. [Q75VT8-1]
DR   CTD; 382062; -.
DR   MGI; MGI:3043001; AB124611.
DR   GeneTree; ENSGT00390000008862; -.
DR   InParanoid; Q75VT8; -.
DR   OrthoDB; 1400769at2759; -.
DR   PhylomeDB; Q75VT8; -.
DR   BioGRID-ORCS; 382062; 5 hits in 71 CRISPR screens.
DR   PRO; PR:Q75VT8; -.
DR   Proteomes; UP000000589; Chromosome 9.
DR   RNAct; Q75VT8; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR041066; C19orf38_Ig.
DR   InterPro; IPR040438; HIDE1.
DR   PANTHER; PTHR36859; PTHR36859; 1.
DR   Pfam; PF17737; Ig_C19orf38; 1.
PE   1: Evidence at protein level;
KW   Alternative splicing; Glycoprotein; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..222
FT                   /note="Protein HIDE1"
FT                   /id="PRO_0000341218"
FT   TOPO_DOM        22..120
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        142..222
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          190..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        48
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         118..147
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.1"
FT                   /id="VSP_034226"
SQ   SEQUENCE   222 AA;  23594 MW;  540EB1734C515459 CRC64;
     MPWTILLFAS GSLAIPAPSI SLVPPYPSSH EDPIYISCTA PGDILGANFT LFRGGEVVQL
     LQAPSDRPDV TFNVTGGGSG GGGEAAGGNF CCQYGVMGEH SQPQLSDFSQ QVQVSFPVPT
     WILALSLSLA GAVLFSGLVA ITVLVRKAKA KNLQKQRERE SCWAQINFTN TDMSFDNSLF
     AISTKMTQED SVATLDSGPR KRPTSASSSP EPPEFSTFRA CQ