ID   HIFC3_HAEIF             Reviewed;         837 AA.
AC   P45998;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Outer membrane usher protein HifC;
DE   Flags: Precursor;
GN   Name=hifC;
OS   Haemophilus influenzae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=86-0295 / LKP serotype 1;
RA   Green B.A., Olmsted S.B.;
RL   Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential for piliation.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the fimbrial export usher family. {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-97 is the initiator.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA61816.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U19730; AAA61816.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; P45998; -.
DR   SMR; P45998; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015473; F:fimbrial usher porin activity; IEA:InterPro.
DR   GO; GO:0009297; P:pilus assembly; IEA:InterPro.
DR   Gene3D; 2.60.40.2070; -; 1.
DR   Gene3D; 2.60.40.2610; -; 1.
DR   Gene3D; 3.10.20.410; -; 1.
DR   InterPro; IPR000015; Fimb_usher.
DR   InterPro; IPR018030; Fimbrial_membr_usher_CS.
DR   InterPro; IPR042186; FimD_plug_dom.
DR   InterPro; IPR025949; PapC-like_C.
DR   InterPro; IPR043142; PapC-like_C_sf.
DR   InterPro; IPR025885; PapC_N.
DR   InterPro; IPR037224; PapC_N_sf.
DR   PANTHER; PTHR30451; PTHR30451; 1.
DR   Pfam; PF13953; PapC_C; 1.
DR   Pfam; PF13954; PapC_N; 1.
DR   Pfam; PF00577; Usher; 1.
DR   SUPFAM; SSF141729; SSF141729; 1.
DR   PROSITE; PS01151; FIMBRIAL_USHER; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Disulfide bond; Fimbrium biogenesis; Membrane; Signal;
KW   Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..837
FT                   /note="Outer membrane usher protein HifC"
FT                   /id="PRO_0000009318"
FT   DISULFID        813..833
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   837 AA;  92766 MW;  5B35F5A58A6ACEBF CRC64;
     MKTKIFPLNK IAFACSLLLA NPLAWAGDQF DASLWGDGSV LGVDFARFNV KNAVLPGRYE
     AQIYVKFEEK GVSDIIFADN PATGRTELCF TPKLQEMLDL MDEAIVKSPN SEDDTCVFAS
     DAIPKGTFEY QSGEMKLKLE LPQALTIRRP RGYIAPSRWQ TGTNAAFANY DINYYRSGNP
     EVKSESLYVG LRSGVNFGNW ALRHSGSFSR FENQSSSGFT DKGKNHYERG DTYLQRDFAL
     LRGNVTVGDF FSTARIGENF GMRGLRIASD DRMLAPSQRG FAPVVRGVAN TNAKVSIKQN
     GYTIYQITVP AGPFVINDLY ASGYSGDLTV EIQESDGKVR SFIVPFSNLA PLMRVGHLRY
     QLAGGRYRID SRTFDERVLQ GVLQYGLTNH LTLNSSLLYT RHYRAGLFGF GLNTPIGAFS
     ADATWSHAEF PLKHVSKNGY SLHGSYSINF NESGTNITLA AYRYSSRDFY TLSDTIGLNR
     TFRQFSGAYL PEIYRPKNQF QVSLSQSLGN WGNLYLSGQT YNYWEKRGTN TQYQVAYSNS
     FHILNYSVNL SQSIDKETGK RDNSIYLSLS LPLGDNHSAD SSYSRSGNDI NQRLGVNGSF
     GERHQWSYGI NASRNNQGYR SYDGNLSHNN SIGSYRASYS RDSLKNRSIS LGASGAVVAH
     KHGITLSQPV GESFAIIHAK DAAGAKVESG ANVSLDYFGN AVMPYTSPYE INYIGINPSD
     AEANVEFEAT ERQIIPRANS ISLVDFRTGK NTMVLFNLTL PNGEPVPMAS TAQDSEGAFV
     GDVVQGGVLF ANKLTQPKGE LIVKWGERES EQCRFQYQVD LDNAQIQSHD IQCKTAK