ID   HIFE1_HAEIF             Reviewed;         435 AA.
AC   P45994;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Minor fimbrial subunit HifE;
DE   Flags: Precursor;
GN   Name=hifE;
OS   Haemophilus influenzae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=727;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Eagan / Serotype B;
RX   PubMed=7927773; DOI=10.1128/iai.62.11.4922-4928.1994;
RA   McCrea K.W., Watson W.J., Gilsdorf J.R., Marrs C.F.;
RT   "Identification of hifD and hifE in the pilus gene cluster of Haemophilus
RT   influenzae type b strain Eagan.";
RL   Infect. Immun. 62:4922-4928(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AM30 (770235) / Serotype B;
RX   PubMed=7997179; DOI=10.1111/j.1365-2958.1994.tb00461.x;
RA   van Ham M.S., van Alphen L., Mooi F.R., van Putten J.P.M.;
RT   "The fimbrial gene cluster of Haemophilus influenzae type b.";
RL   Mol. Microbiol. 13:673-684(1994).
CC   -!- FUNCTION: May be a minor structural protein required for pilus
CC       biogenesis. May be the adhesive component in the pili.
CC   -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR   EMBL; U13254; AAA61542.1; -; Genomic_DNA.
DR   EMBL; Z33502; CAA83904.1; -; Genomic_DNA.
DR   PIR; S68865; S68865.
DR   AlphaFoldDB; P45994; -.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   3: Inferred from homology;
KW   Fimbrium; Signal.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255"
FT   CHAIN           32..435
FT                   /note="Minor fimbrial subunit HifE"
FT                   /id="PRO_0000009223"
SQ   SEQUENCE   435 AA;  48852 MW;  420C733661DE7D67 CRC64;
     MKTLTTYAKY FTPISKIAFL FCFLMGNIAE ATIKRAKFTN GFSGINRIIT YTFEGSSTMI
     ASATTPEQIL FSKARDNTVI DPSYSNNVQQ WSVFNNWIDT TVSGDTGYSF AGFSCVSNPC
     AQMQLPLRFY LDSAILEATS MRSADNQVIF KIRQHPELGV SFQLGMKKGI EDVKWLSNLQ
     QEDFLLTTLQ IYFGDAADIS FKVRAKLHLL KLPTENTELP TMKLNLGQIK LQSWGINNWG
     RTKVSYRVQD VGSLNVQLKT PKIYFIQQQR QCILNSTYKK IPVTLKSVKK REFETNTEIE
     GGQFKLRVNC EDTTYNKFNG KWLFPVVKVT FRGEDGTMND GTNELLRTQT GTGQATGVSL
     KIKRDSGNGD SVKYGLDSAN MNNHGQFELK KQPSPAGGDQ SAEETFKVYY VKDTTRGALT
     EGKVKAAATF TMSYQ