ID   HILD_SALTS              Reviewed;         309 AA.
AC   E1WAC0; P41782; Q9X5C3;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Transcriptional regulator HilD;
GN   Name=hilD; OrderedLocusNames=SL1344_2855;
OS   Salmonella typhimurium (strain SL1344).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=216597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SL1344;
RX   PubMed=10320584; DOI=10.1046/j.1365-2958.1999.01381.x;
RA   Schechter L.M., Damrauer S.M., Lee C.A.;
RT   "Two AraC/XylS family members can independently counteract the effect of
RT   repressing sequences upstream of the hilA promoter.";
RL   Mol. Microbiol. 32:629-642(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL1344;
RX   PubMed=22538806; DOI=10.1073/pnas.1201061109;
RA   Kroger C., Dillon S.C., Cameron A.D., Papenfort K., Sivasankaran S.K.,
RA   Hokamp K., Chao Y., Sittka A., Hebrard M., Handler K., Colgan A.,
RA   Leekitcharoenphon P., Langridge G.C., Lohan A.J., Loftus B., Lucchini S.,
RA   Ussery D.W., Dorman C.J., Thomson N.R., Vogel J., Hinton J.C.;
RT   "The transcriptional landscape and small RNAs of Salmonella enterica
RT   serovar Typhimurium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:E1277-E1286(2012).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF124398; AAD21081.1; -; Genomic_DNA.
DR   EMBL; FQ312003; CBW18953.1; -; Genomic_DNA.
DR   RefSeq; WP_000432699.1; NZ_QASL01000017.1.
DR   AlphaFoldDB; E1WAC0; -.
DR   SMR; E1WAC0; -.
DR   EnsemblBacteria; CBW18953; CBW18953; SL1344_2855.
DR   KEGG; sey:SL1344_2855; -.
DR   PATRIC; fig|216597.6.peg.3176; -.
DR   HOGENOM; CLU_000445_81_4_6; -.
DR   OMA; TIYCEEP; -.
DR   BioCyc; SENT216597:SL1344_RS14885-MON; -.
DR   Proteomes; UP000008962; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR018062; HTH_AraC-typ_CS.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..309
FT                   /note="Transcriptional regulator HilD"
FT                   /id="PRO_0000405419"
FT   DOMAIN          209..306
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        226..247
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        273..296
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   309 AA;  35218 MW;  B827FC4B3785358E CRC64;
     MENVTFVSNS HQRPAADNLQ KLKSLLTNTR QQIKSQTQQV TIKNLYVSSF TLVCFRSGKL
     TISNNHDTIY CDEPGMLVLK KEQVVNVTLE EVNGHMDFDI LEIPTQRLGA LYALIPNEQQ
     TKMAVPTEKA QKIFYTPDFP ARREVFEHLK TAFSCTKDTS KGCSNCNNKS CIENEELIPY
     FLLFLLTAFL RLPESYEIIL SSAQITLKER VYNIISSSPS RQWKLTDVAD HIFMSTSTLK
     RKLAEEGTSF SDIYLSARMN QAAKLLRIGN HNVNAVALKC GYDSTSYFIQ CFKKYFKTTP
     STFIKMANH