HILD_SALTY
ID HILD_SALTY Reviewed; 309 AA.
AC P0CL08; P41782; Q9X5C3;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 08-MAR-2011, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=Transcriptional regulator HilD;
GN Name=hilD; OrderedLocusNames=STM2875;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-225.
RC STRAIN=ATCC 14028s / SGSG 2262;
RX PubMed=7476203; DOI=10.1111/j.1365-2958.1995.mmi_17010169.x;
RA Pegues D.A., Hantman M.J., Behlau I., Miller S.I.;
RT "PhoP/PhoQ transcriptional repression of Salmonella typhimurium invasion
RT genes: evidence for a role in protein secretion.";
RL Mol. Microbiol. 17:169-181(1995).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB60187.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE006468; AAL21755.1; -; Genomic_DNA.
DR EMBL; U21676; AAB60187.1; ALT_FRAME; Genomic_DNA.
DR PIR; S69787; S69787.
DR RefSeq; NP_461796.1; NC_003197.2.
DR RefSeq; WP_000432699.1; NC_003197.2.
DR AlphaFoldDB; P0CL08; -.
DR SMR; P0CL08; -.
DR STRING; 99287.STM2875; -.
DR PaxDb; P0CL08; -.
DR EnsemblBacteria; AAL21755; AAL21755; STM2875.
DR GeneID; 1254398; -.
DR KEGG; stm:STM2875; -.
DR PATRIC; fig|99287.12.peg.3031; -.
DR HOGENOM; CLU_000445_81_4_6; -.
DR OMA; TIYCEEP; -.
DR PhylomeDB; P0CL08; -.
DR BioCyc; SENT99287:STM2875-MON; -.
DR PHI-base; PHI:635; -.
DR PHI-base; PHI:7270; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR Pfam; PF12833; HTH_18; 1.
DR PRINTS; PR00032; HTHARAC.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..309
FT /note="Transcriptional regulator HilD"
FT /id="PRO_0000194524"
FT DOMAIN 209..306
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 226..247
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 273..296
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT CONFLICT 182..183
FT /note="Missing (in Ref. 2; AAB60187)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 309 AA; 35218 MW; B827FC4B3785358E CRC64;
MENVTFVSNS HQRPAADNLQ KLKSLLTNTR QQIKSQTQQV TIKNLYVSSF TLVCFRSGKL
TISNNHDTIY CDEPGMLVLK KEQVVNVTLE EVNGHMDFDI LEIPTQRLGA LYALIPNEQQ
TKMAVPTEKA QKIFYTPDFP ARREVFEHLK TAFSCTKDTS KGCSNCNNKS CIENEELIPY
FLLFLLTAFL RLPESYEIIL SSAQITLKER VYNIISSSPS RQWKLTDVAD HIFMSTSTLK
RKLAEEGTSF SDIYLSARMN QAAKLLRIGN HNVNAVALKC GYDSTSYFIQ CFKKYFKTTP
STFIKMANH
