ID   HIN_SALAE               Reviewed;         190 AA.
AC   Q02869;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=DNA-invertase;
GN   Name=hin;
OS   Salmonella abortus-equi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=607;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8423149; DOI=10.1128/jb.175.3.758-766.1993;
RA   Okazaki N., Matsuo S., Saito K., Tominaga A., Enomoto M.;
RT   "Conversion of the Salmonella phase 1 flagellin gene fliC to the phase 2
RT   gene fljB on the Escherichia coli K-12 chromosome.";
RL   J. Bacteriol. 175:758-766(1993).
CC   -!- FUNCTION: A DNA fragment of approximately 900 base pairs, adjacent to
CC       the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin,
CC       can exist in either orientation with respect to fljB. The orientation
CC       of the inversion region controls expression of fljB. The hin gene
CC       occupies about two-thirds of the inversion region; it is required for
CC       the inversion of the fljB controlling region.
CC   -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC       {ECO:0000305}.
CC   -!- CAUTION: The sequence given here is inactive. {ECO:0000305}.
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DR   EMBL; D13690; BAA02847.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q02869; -.
DR   SMR; Q02869; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1390; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006118; Recombinase_CS.
DR   InterPro; IPR006119; Resolv_N.
DR   InterPro; IPR036162; Resolvase-like_N_sf.
DR   InterPro; IPR006120; Resolvase_HTH_dom.
DR   Pfam; PF02796; HTH_7; 1.
DR   Pfam; PF00239; Resolvase; 1.
DR   SMART; SM00857; Resolvase; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53041; SSF53041; 1.
DR   PROSITE; PS00397; RECOMBINASES_1; 1.
DR   PROSITE; PS00398; RECOMBINASES_2; 1.
DR   PROSITE; PS51736; RECOMBINASES_3; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA invertase; DNA recombination; DNA-binding.
FT   CHAIN           1..190
FT                   /note="DNA-invertase"
FT                   /id="PRO_0000196358"
FT   DOMAIN          2..135
FT                   /note="Resolvase/invertase-type recombinase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
FT   DNA_BIND        162..181
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        10
FT                   /note="O-(5'-phospho-DNA)-serine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
SQ   SEQUENCE   190 AA;  21419 MW;  64CD92BD5BA40F7B CRC64;
     MATIGYIRVS TIDQNIDLQR NALTSANCDR IFEDRISGKI ANRPGLKRAL KYVNKGDTLV
     VWKLDRLGRS VKNLVALISE LHERGAHFHS LTDSIDTSSA MGRFFFHVMS APAEMERELI
     VERTLAGLAA ARAQGRLGGH PRAINRHEQE QISRLLEKGH PRQQLAIIFG IGVSTLYRYF
     PASRIKKRMN