ID   HIP10_ARATH             Reviewed;         111 AA.
AC   F4KHL6; Q9LTE5;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Heavy metal-associated isoprenylated plant protein 10 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
DE            Short=AtHIP10 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
DE   Flags: Precursor;
GN   Name=HIPP10 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
GN   OrderedLocusNames=At5g52720 {ECO:0000312|Araport:AT5G52720};
GN   ORFNames=F6N7.21 {ECO:0000312|EMBL:BAA98090.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RA   Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL   Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=21072340; DOI=10.1039/c003484c;
RA   Tehseen M., Cairns N., Sherson S., Cobbett C.S.;
RT   "Metallochaperone-like genes in Arabidopsis thaliana.";
RL   Metallomics 2:556-564(2010).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=23368984; DOI=10.1111/febs.12159;
RA   de Abreu-Neto J.B., Turchetto-Zolet A.C., de Oliveira L.F., Zanettini M.H.,
RA   Margis-Pinheiro M.;
RT   "Heavy metal-associated isoprenylated plant protein (HIPP):
RT   characterization of a family of proteins exclusive to plants.";
RL   FEBS J. 280:1604-1616(2013).
CC   -!- FUNCTION: Probable heavy-metal-binding protein.
CC       {ECO:0000250|UniProtKB:Q9LZF1}.
CC   -!- SIMILARITY: Belongs to the HIPP family. {ECO:0000305}.
CC   -!- CAUTION: Contains an apparent HMA-like domain but lacks the core
CC       conserved Cys-X-X-Cys motif. {ECO:0000305|PubMed:21072340}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA98090.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB025606; BAA98090.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002688; AED96253.1; -; Genomic_DNA.
DR   RefSeq; NP_200084.2; NM_124650.3.
DR   AlphaFoldDB; F4KHL6; -.
DR   SMR; F4KHL6; -.
DR   PaxDb; F4KHL6; -.
DR   PRIDE; F4KHL6; -.
DR   EnsemblPlants; AT5G52720.1; AT5G52720.1; AT5G52720.
DR   GeneID; 835349; -.
DR   Gramene; AT5G52720.1; AT5G52720.1; AT5G52720.
DR   KEGG; ath:AT5G52720; -.
DR   Araport; AT5G52720; -.
DR   TAIR; locus:2149674; AT5G52720.
DR   HOGENOM; CLU_2267473_0_0_1; -.
DR   PRO; PR:F4KHL6; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; F4KHL6; baseline and differential.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   PROSITE; PS50846; HMA_2; 1.
PE   3: Inferred from homology;
KW   Lipoprotein; Metal-binding; Methylation; Prenylation; Reference proteome.
FT   CHAIN           1..108
FT                   /note="Heavy metal-associated isoprenylated plant protein
FT                   10"
FT                   /id="PRO_0000437809"
FT   PROPEP          109..111
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000437810"
FT   DOMAIN          1..68
FT                   /note="HMA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00280"
FT   REGION          68..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         108
FT                   /note="Cysteine methyl ester"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SZN7"
FT   LIPID           108
FT                   /note="S-farnesyl cysteine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SZN7"
SQ   SEQUENCE   111 AA;  12579 MW;  8595B63B239402B2 CRC64;
     MQETVVFEWG SFDVRTKEKA MKVVCEFPGV TVIDVKERGK LKVTGQFDKF IMTKKLKKIC
     DYVDITAVGP EGQPAQNRNP VKKPEPKVIR GRPYPPQKKT PGKNSDECII L