HIP17_ARATH
ID HIP17_ARATH Reviewed; 264 AA.
AC Q9FVS0;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Heavy metal-associated isoprenylated plant protein 17 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
DE Short=AtHIP17 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
DE Flags: Precursor;
GN Name=HIPP17 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
GN OrderedLocusNames=At1g57780 {ECO:0000312|Araport:AT1G57780};
GN ORFNames=F12K22.17 {ECO:0000312|EMBL:AAG29232.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=21072340; DOI=10.1039/c003484c;
RA Tehseen M., Cairns N., Sherson S., Cobbett C.S.;
RT "Metallochaperone-like genes in Arabidopsis thaliana.";
RL Metallomics 2:556-564(2010).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=23368984; DOI=10.1111/febs.12159;
RA de Abreu-Neto J.B., Turchetto-Zolet A.C., de Oliveira L.F., Zanettini M.H.,
RA Margis-Pinheiro M.;
RT "Heavy metal-associated isoprenylated plant protein (HIPP):
RT characterization of a family of proteins exclusive to plants.";
RL FEBS J. 280:1604-1616(2013).
CC -!- FUNCTION: Probable heavy-metal-binding protein.
CC {ECO:0000250|UniProtKB:Q9LZF1}.
CC -!- SIMILARITY: Belongs to the HIPP family. {ECO:0000305}.
CC -!- CAUTION: The HMA domain lacks the core conserved Cys-X-X-Cys motif.
CC {ECO:0000305|PubMed:21072340}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC079732; AAG29232.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33466.1; -; Genomic_DNA.
DR PIR; B96612; B96612.
DR RefSeq; NP_176089.1; NM_104573.2.
DR AlphaFoldDB; Q9FVS0; -.
DR SMR; Q9FVS0; -.
DR STRING; 3702.AT1G57780.1; -.
DR PaxDb; Q9FVS0; -.
DR PRIDE; Q9FVS0; -.
DR EnsemblPlants; AT1G57780.1; AT1G57780.1; AT1G57780.
DR GeneID; 842153; -.
DR Gramene; AT1G57780.1; AT1G57780.1; AT1G57780.
DR KEGG; ath:AT1G57780; -.
DR Araport; AT1G57780; -.
DR TAIR; locus:2009390; AT1G57780.
DR eggNOG; KOG1603; Eukaryota.
DR HOGENOM; CLU_039886_3_1_1; -.
DR OMA; PETSIME; -.
DR OrthoDB; 1723636at2759; -.
DR PhylomeDB; Q9FVS0; -.
DR PRO; PR:Q9FVS0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FVS0; baseline and differential.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR044577; HIPP4/7/8/17/18/19.
DR InterPro; IPR006121; HMA_dom.
DR PANTHER; PTHR46195; PTHR46195; 1.
DR Pfam; PF00403; HMA; 1.
DR PROSITE; PS50846; HMA_2; 2.
PE 3: Inferred from homology;
KW Coiled coil; Lipoprotein; Metal-binding; Methylation; Prenylation;
KW Reference proteome; Repeat.
FT CHAIN 1..261
FT /note="Heavy metal-associated isoprenylated plant protein
FT 17"
FT /id="PRO_0000437823"
FT PROPEP 262..264
FT /note="Removed in mature form"
FT /evidence="ECO:0000305"
FT /id="PRO_0000437824"
FT DOMAIN 32..95
FT /note="HMA 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00280"
FT DOMAIN 133..204
FT /note="HMA 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00280"
FT COILED 185..218
FT /evidence="ECO:0000255"
FT MOD_RES 261
FT /note="Cysteine methyl ester"
FT /evidence="ECO:0000250|UniProtKB:Q9SZN7"
FT LIPID 261
FT /note="S-farnesyl cysteine"
FT /evidence="ECO:0000250|UniProtKB:Q9SZN7"
SQ SEQUENCE 264 AA; 30646 MW; 1970C5CA268758A3 CRC64;
MGCWLKQPQG ITTMMGCWLT KSRENILDNV IVTDAKLKIS MNFEDCAKKI RKVACQFEVK
SCITDIDDQK VLVSGDFNLH KLVKTLKKKT GKKIEIVTKN EKSSEDKVDD TVQNEDSKDE
IVPQNADKPE TSIMEVEFDI PFLCEKYEKD FGKVISKCTG VETYVVDLEN KKVVVIGNFD
KDELSRKLNK KMHQKIKKAE KERQEWESEM MLREAEEEKR LADIYEEIDK DRNVSLNPIT
DYEKEMAKHY YMFSDENPNA CSIS
