ID   HIP47_ARATH             Reviewed;         118 AA.
AC   F4JDJ0;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Heavy metal-associated isoprenylated plant protein 47 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
DE            Short=AtHIP47 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
DE   Flags: Precursor;
GN   Name=HIPP47 {ECO:0000303|PubMed:21072340, ECO:0000303|PubMed:23368984};
GN   OrderedLocusNames=At3g20180 {ECO:0000312|Araport:AT3G20180};
GN   ORFNames=MAL21 {ECO:0000312|EMBL:AP000383};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=21072340; DOI=10.1039/c003484c;
RA   Tehseen M., Cairns N., Sherson S., Cobbett C.S.;
RT   "Metallochaperone-like genes in Arabidopsis thaliana.";
RL   Metallomics 2:556-564(2010).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=23368984; DOI=10.1111/febs.12159;
RA   de Abreu-Neto J.B., Turchetto-Zolet A.C., de Oliveira L.F., Zanettini M.H.,
RA   Margis-Pinheiro M.;
RT   "Heavy metal-associated isoprenylated plant protein (HIPP):
RT   characterization of a family of proteins exclusive to plants.";
RL   FEBS J. 280:1604-1616(2013).
CC   -!- FUNCTION: Heavy-metal-binding protein. {ECO:0000250|UniProtKB:Q9LZF1}.
CC   -!- SIMILARITY: Belongs to the HIPP family. {ECO:0000305}.
CC   -!- CAUTION: Contains an apparent HMA-like domain but lacks the core
CC       conserved Cys-X-X-Cys motif. {ECO:0000305|PubMed:21072340}.
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DR   EMBL; AP000383; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002686; AEE76344.1; -; Genomic_DNA.
DR   RefSeq; NP_188653.1; NM_112909.1.
DR   AlphaFoldDB; F4JDJ0; -.
DR   SMR; F4JDJ0; -.
DR   PaxDb; F4JDJ0; -.
DR   PRIDE; F4JDJ0; -.
DR   DNASU; 821562; -.
DR   EnsemblPlants; AT3G20180.1; AT3G20180.1; AT3G20180.
DR   GeneID; 821562; -.
DR   Gramene; AT3G20180.1; AT3G20180.1; AT3G20180.
DR   KEGG; ath:AT3G20180; -.
DR   Araport; AT3G20180; -.
DR   TAIR; locus:2087580; AT3G20180.
DR   HOGENOM; CLU_092610_2_3_1; -.
DR   InParanoid; F4JDJ0; -.
DR   PhylomeDB; F4JDJ0; -.
DR   PRO; PR:F4JDJ0; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; F4JDJ0; baseline and differential.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR042885; HIP47.
DR   InterPro; IPR044296; HIPP16/46/47.
DR   PANTHER; PTHR46371; PTHR46371; 1.
DR   PANTHER; PTHR46371:SF17; PTHR46371:SF17; 1.
DR   PROSITE; PS50846; HMA_2; 1.
PE   3: Inferred from homology;
KW   Lipoprotein; Metal-binding; Methylation; Prenylation; Reference proteome.
FT   CHAIN           1..115
FT                   /note="Heavy metal-associated isoprenylated plant protein
FT                   47"
FT                   /id="PRO_0000437866"
FT   PROPEP          116..118
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000437867"
FT   DOMAIN          1..67
FT                   /note="HMA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00280"
FT   MOD_RES         115
FT                   /note="Cysteine methyl ester"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SZN7"
FT   LIPID           115
FT                   /note="S-farnesyl cysteine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9SZN7"
SQ   SEQUENCE   118 AA;  12888 MW;  2CDB2C100A1DF71D CRC64;
     MRIKLSVNSE KCRKKAMQVA VAADGVTSVA MEGEFQDELV VVGDGVDSAS LIMALRKKAC
     HVTLETLEEV KKPQVEEKSI TPHCCIAQCP VVSNEQPRPE VYRIVHDSYG PTTGCLVM