ID   HIP_MYTED               Reviewed;         213 AA.
AC   P83425;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Heavy metal-binding protein HIP;
OS   Mytilus edulis (Blue mussel).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Mytilida; Mytiloidea; Mytilidae; Mytilinae;
OC   Mytilus.
OX   NCBI_TaxID=6550 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, AND TISSUE SPECIFICITY.
RC   TISSUE=Plasma;
RA   Schneeweiss H., Schmalmack W., Luedeking A., Jarck F., Behlich L.-K.,
RA   Buck F.;
RL   Submitted (JUL-2002) to UniProtKB.
CC   -!- FUNCTION: Binds heavy metals. May function as a carrier of divalent
CC       cations in plasma. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Pallium, gill and liver. {ECO:0000269|Ref.1,
CC       ECO:0000305}.
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DR   AlphaFoldDB; P83425; -.
DR   SMR; P83425; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.40; -; 1.
DR   InterPro; IPR001073; C1q_dom.
DR   InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR   Pfam; PF00386; C1q; 1.
DR   PRINTS; PR00007; COMPLEMNTC1Q.
DR   SMART; SM00110; C1Q; 1.
DR   SUPFAM; SSF49842; SSF49842; 1.
DR   PROSITE; PS50871; C1Q; 1.
PE   1: Evidence at protein level;
KW   Cadmium; Copper; Direct protein sequencing; Metal-binding; Secreted; Zinc.
FT   CHAIN           1..213
FT                   /note="Heavy metal-binding protein HIP"
FT                   /id="PRO_0000143959"
FT   DOMAIN          80..213
FT                   /note="C1q"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00368"
SQ   SEQUENCE   213 AA;  24289 MW;  175842EE68952761 CRC64;
     NPVDDHQNDD HHDAPIVGHH DAFLKAEFDL TSLNADLEKF IHHEIEKEIH DVENHTEHNK
     HEIDALHLEI KQLHEEVEYF KSHHVAFSAE LTHPIENLGA EEIAHFDKVR VNSGDAYHVD
     TGKFVAPEEG FFYFSVTICT KRDSILEMAL HVNDHDEMII HADAEHLELG CASNSEIVHL
     QKGDHVEVVK HGADGVPPFY IHTMSTFTGF MLH