HIR3_CHAGB
ID HIR3_CHAGB Reviewed; 1982 AA.
AC Q2H1Q1;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Histone transcription regulator 3 homolog;
GN Name=HIR3; ORFNames=CHGG_04295;
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- FUNCTION: Has a role in a nucleosome assembly pathway that is required
CC for the integrity of heterochromatin and proper chromosome segregation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the HIR3 family. {ECO:0000305}.
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DR EMBL; CH408032; EAQ87676.1; -; Genomic_DNA.
DR RefSeq; XP_001223509.1; XM_001223508.1.
DR AlphaFoldDB; Q2H1Q1; -.
DR STRING; 38033.XP_001223509.1; -.
DR EnsemblFungi; EAQ87676; EAQ87676; CHGG_04295.
DR GeneID; 4392648; -.
DR eggNOG; ENOG502QQX4; Eukaryota.
DR HOGENOM; CLU_001419_0_0_1; -.
DR InParanoid; Q2H1Q1; -.
DR OMA; WETWYRL; -.
DR OrthoDB; 72175at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0006336; P:DNA replication-independent chromatin assembly; IEA:InterPro.
DR InterPro; IPR033053; Hir3/CABIN1.
DR PANTHER; PTHR15502; PTHR15502; 1.
PE 3: Inferred from homology;
KW Chromosome partition; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..1982
FT /note="Histone transcription regulator 3 homolog"
FT /id="PRO_0000256198"
FT REGION 333..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1688..1776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1791..1982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1688..1702
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1741..1755
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1834..1851
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1894..1908
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1909..1951
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1967..1982
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1982 AA; 220916 MW; EABC23B6859337F6 CRC64;
MAAFSAINVE PEENIDEEVD TTKDLQVDDA LKLFQNALKL HAQGPQSFDQ AADAYDALFE
SEIFKYPESK TDYERFEAGQ DGTLATEPVF AQGLPPVGAD VDGIGSSLPQ ALYLSHKNHG
QFVIDRIKHK VRKSTKKREP LLKDAGVQKD AQRALDDFCV ALDRDPSDAE LWRKTARVAA
FLKSARINRY SLEAAIELED DPAVEEVDPP SLAEGFAGEQ LKQQLQVLGD DMALTHPIMN
PFVHREMPPY LARFMDPMPF LPDPTKRLAV KELRDTEIET ARSVLPISIP SWSELGAAIV
RFVTKEGLAG QGVLIQLPDT DEQEDVQMEV DMQLQPEEPS SQSGTPDEVV EAEEAVAEPP
SEEATVEGLT SAPAPESSPT DEQASKDPNN SISTRKRSQS AAGIPDALED DAADVKRSKR
TRRRDTAVEE VMDSATFLAS QLQPLQAADQ NLFQTTKNLL ENLGVTDQVT LGRIAEVLDS
CAADDRTGKI QNQATVDLSH SITHFDEDTG AVLLSKRELP QLSLSAFLEH AKTGSQRAQE
ASAFDDSRGL KSFVENVNQG WNTIHDIAYK YVKALVKTYT EYKWPDQLRT AVIDVTGRLE
GSIYDSFAYE LELSPKDVQG ETISELAGLA QTLFELHLDV YDHITDPNST ADQEAKLEAK
CRVDRWADMA GEVIRLRTLE PDDPIALRFL WASVASTTMA KGTPRDHVLN CWHSLRDFLL
GSAATEVNLV NNTTMPEIST AAAEREISKL TTMDFFLGLF QEDNGNPVAV VESLEPVLNP
EGVYITIPAT LKQADAGGDA PSDKPGKLPI AECASQELTD LWKFLKGSNT ELRLLLWSRL
GEAYGKIQYT TKQFSCFLRS IETVISDLES DDYLHSTDEP RRNQFMSLLK ALDDLIIQSL
HLALNDNSSF DIMDDDHLRS SMSALAKVSC MLHVAAMFED ETRIGMKPAP ASTSDLRSFL
NKLQEMQVRT WSLQYTMLKV GLNQHPELFP KPENDLADYL AAVHQVLGLR KCCKSSNKIF
LKMMRVELLK QKNIDNWEDY LGQVLYDLHG LKLGVGIWEV QDHGCEPENL EKRQALQLVG
KVTMLANRMS MKDLLKSDLK TTIERMQQAI GSAKSSPQMA HNLRNYSEYL KAPIHPLHLY
QALTGSVDLD AVTINTPESA PAKQGWFFLL GMIALTKFKG VDLNRRQTPG ATDDLRIGAT
FLRLQLQYTP DRWDAWFRLA ECFDYELDES VLWTADKMNK ERAELVKFQR NAIHSYIMAL
SHSYAWASDP AVLTSLEDDE EALYDMFHEF GMRMYSSSRS PFAMEPFQHA EQNRFFIEAE
GAGTYKRIVH NEMTDYQVWK FAAHLFRKAM VGKPKDWKNP YMVAKCLWKM YQKPPEELDE
KNRLRRPTVQ AVIDALEKTI EVVSSLPKPR HGQDPILEPH YKIVSVVHKL VMRGDMEIQA
AANVLQHQPY APDRGQEISV VNAEDWEAYV VRCLKYLRDK DKSNWQHRII MRHARILFDE
DTDPSDNESS AAAKAAFNVL RESMFTKTMV MNVWKCDAER PGRHHVYTEQ YIRYMVRVLD
VMKDRVSLEA VLRRIRKKGA DFYHFNELWQ FGVLAYVKLL RRTFEVPLTE EDAFKTLSQE
EFDTVGEKIT AWSTTPAAED NAALTAMKEA VEIKKLNSNL MKAGPIDDLI TDCYSAIYLH
VKPDLLDSDQ QKLPHHPPGD PESKPDSSNP KSTSLLLHAL ITRDKDKDMT PSALSSLRAN
SEQPDRDKSE RHSLAGDAPP RAASGRAGGG IRRPNILRKA EQAVQAVLRA AEMPPRSVGG
ATNGAAGGGK TRSRMGSVSN ARAGGRAAGE GSGDESGEDE EEAEEGDVEM KDVGDDTGGG
GGRRVVVERS VDAGTVKGAA GGDSSYEESD PEGEGESGDR HDHEGEGEGE MEVEQEAGQE
EEEGGVGEEH GGDDEIGDDD ETEEEHEEGD EGREEGAAPA LPEPVMEDAD ATEEEDEEDE
GE
