3SO1_NAJAT
ID 3SO1_NAJAT Reviewed; 86 AA.
AC Q9W717;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Neurotoxin-like protein NTL2 {ECO:0000312|EMBL:CAB45156.1};
DE Flags: Precursor;
OS Naja atra (Chinese cobra).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Naja.
OX NCBI_TaxID=8656;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom gland;
RA Qian Y.-C., Fan C.-Y., Gong Y., Yang S.-L.;
RT "The polygene family of neurotoxins from Naja naja atra.";
RL Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC subfamily. Orphan group I sub-subfamily. {ECO:0000305}.
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DR EMBL; AJ006139; CAB45156.1; -; mRNA.
DR AlphaFoldDB; Q9W717; -.
DR SMR; Q9W717; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR CDD; cd00206; snake_toxin; 1.
DR Gene3D; 2.10.60.10; -; 1.
DR InterPro; IPR003571; Snake_3FTx.
DR InterPro; IPR045860; Snake_toxin-like_sf.
DR InterPro; IPR018354; Snake_toxin_con_site.
DR InterPro; IPR035076; Toxin/TOLIP.
DR Pfam; PF00087; Toxin_TOLIP; 1.
DR SUPFAM; SSF57302; SSF57302; 1.
DR PROSITE; PS00272; SNAKE_TOXIN; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..21
FT /evidence="ECO:0000250"
FT CHAIN 22..86
FT /note="Neurotoxin-like protein NTL2"
FT /id="PRO_0000035473"
FT DISULFID 24..45
FT /evidence="ECO:0000250|UniProtKB:P60301"
FT DISULFID 38..63
FT /evidence="ECO:0000250|UniProtKB:P60301"
FT DISULFID 67..78
FT /evidence="ECO:0000250|UniProtKB:P60301"
FT DISULFID 79..84
FT /evidence="ECO:0000250|UniProtKB:P60301"
SQ SEQUENCE 86 AA; 9695 MW; CFEB5E8BAAAED4BF CRC64;
MKTLLLSLVV VTIVCLDLGY TRLCLSDYSI FSETIEICPD GHNFCFKKFP KGITRLPWVI
RGCAATCPKA EARVYVDCCA RDKCNR