ID   3SO3_BUNMU              Reviewed;          86 AA.
AC   Q9YGI8; E2IU17;
DT   25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Short neurotoxin homolog NTL4;
DE   Flags: Precursor;
OS   Bungarus multicinctus (Many-banded krait).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Bungarinae; Bungarus.
OX   NCBI_TaxID=8616;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=9844743; DOI=10.1080/15216549800204362;
RA   Qian Y.-C., Fan C.-Y., Gong Y., Yang S.-L.;
RT   "cDNA cloning and sequence analysis of six neurotoxin-like proteins from
RT   Chinese continental banded krait.";
RL   Biochem. Mol. Biol. Int. 46:821-828(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 57-86.
RA   Wang W., Jiang Y., Li Y., Xu X.;
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- MISCELLANEOUS: Is classified as a P-type cytotoxin, since a proline
CC       residue stands at position 54 (Pro-31 in standard classification).
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC       subfamily. Orphan group III sub-subfamily. {ECO:0000305}.
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DR   EMBL; AJ006137; CAA06887.1; -; mRNA.
DR   EMBL; HM597750; ADN67592.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9YGI8; -.
DR   SMR; Q9YGI8; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   CDD; cd00206; snake_toxin; 1.
DR   Gene3D; 2.10.60.10; -; 1.
DR   InterPro; IPR003571; Snake_3FTx.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   InterPro; IPR018354; Snake_toxin_con_site.
DR   InterPro; IPR035076; Toxin/TOLIP.
DR   Pfam; PF00087; Toxin_TOLIP; 1.
DR   SUPFAM; SSF57302; SSF57302; 1.
DR   PROSITE; PS00272; SNAKE_TOXIN; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Secreted; Signal; Toxin.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250"
FT   CHAIN           22..86
FT                   /note="Short neurotoxin homolog NTL4"
FT                   /id="PRO_0000035428"
FT   DISULFID        24..45
FT                   /evidence="ECO:0000250|UniProtKB:P83346"
FT   DISULFID        38..63
FT                   /evidence="ECO:0000250|UniProtKB:P83346"
FT   DISULFID        67..78
FT                   /evidence="ECO:0000250|UniProtKB:P83346"
FT   DISULFID        79..84
FT                   /evidence="ECO:0000250|UniProtKB:P83346"
SQ   SEQUENCE   86 AA;  9519 MW;  9B052041C50173C1 CRC64;
     MKTLLLTLVV VTIICLDLGY TRKCLIKYSQ ANESSKTCPS GQLLCLKKWE IGNPSGKEVK
     RGCVATCPKP KKNEIIQCCA KDKCNK