ID   3SO3_CAURH              Reviewed;          61 AA.
AC   P84716;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Neurotoxin-like protein 1;
OS   Causus rhombeatus (Rhombic night adder).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Viperidae; Viperinae; Causus.
OX   NCBI_TaxID=44735;
RN   [1]
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, AND MASS SPECTROMETRY.
RC   TISSUE=Venom;
RA   Doley R., Kini R.M.;
RL   Submitted (NOV-2005) to UniProtKB.
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   TISSUE=Venom;
RX   PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA   Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA   McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA   Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA   de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA   Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA   Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA   Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT   "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT   snake venom system.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- MASS SPECTROMETRY: Mass=7034.85; Mass_error=0.07; Method=Electrospray;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC       subfamily. Orphan group III sub-subfamily. {ECO:0000305}.
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DR   AlphaFoldDB; P84716; -.
DR   SMR; P84716; -.
DR   TopDownProteomics; P84716; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   CDD; cd00206; snake_toxin; 1.
DR   Gene3D; 2.10.60.10; -; 1.
DR   InterPro; IPR003571; Snake_3FTx.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   InterPro; IPR018354; Snake_toxin_con_site.
DR   SUPFAM; SSF57302; SSF57302; 1.
DR   PROSITE; PS00272; SNAKE_TOXIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT   CHAIN           1..61
FT                   /note="Neurotoxin-like protein 1"
FT                   /evidence="ECO:0000269|Ref.1"
FT                   /id="PRO_0000093536"
FT   DISULFID        3..24
FT                   /evidence="ECO:0000250|UniProtKB:P83346"
FT   DISULFID        17..38
FT                   /evidence="ECO:0000250|UniProtKB:P83346"
FT   DISULFID        42..53
FT                   /evidence="ECO:0000250|UniProtKB:P83346"
FT   DISULFID        54..59
FT                   /evidence="ECO:0000250|UniProtKB:P83346"
SQ   SEQUENCE   61 AA;  7042 MW;  937E7E7C7E6F4ECA CRC64;
     MKCLTKYSRV SETSQTCHVW QNLCFKKWQK GKKVSRGCTA TCPKPKKDEV IQCCAKDKCN
     K