ID   3SO61_HEMHA             Reviewed;          61 AA.
AC   P25676;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Weak toxin CM-1c;
OS   Hemachatus haemachatus (Rinkhals) (Sepedon haemachatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Elapinae; Hemachatus.
OX   NCBI_TaxID=8626;
RN   [1]
RP   PROTEIN SEQUENCE, TOXIC DOSE, AND SUBCELLULAR LOCATION.
RC   TISSUE=Venom;
RA   Joubert F.J., Taljaard N.;
RT   "Complete primary structure of toxin CM-1C from Hemachatus haemachatus
RT   (Ringhals) venom.";
RL   S. Afr. J. Chem. 32:73-77(1979).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- TOXIC DOSE: LD(50) is 54 mg/kg by intravenous injection.
CC       {ECO:0000269|Ref.1}.
CC   -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC       subfamily. Orphan group VI sub-subfamily. {ECO:0000305}.
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DR   AlphaFoldDB; P25676; -.
DR   SMR; P25676; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   CDD; cd00206; snake_toxin; 1.
DR   Gene3D; 2.10.60.10; -; 1.
DR   InterPro; IPR003571; Snake_3FTx.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   InterPro; IPR018354; Snake_toxin_con_site.
DR   SUPFAM; SSF57302; SSF57302; 1.
DR   PROSITE; PS00272; SNAKE_TOXIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT   CHAIN           1..61
FT                   /note="Weak toxin CM-1c"
FT                   /evidence="ECO:0000269|Ref.1"
FT                   /id="PRO_0000093625"
FT   DISULFID        3..21
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        14..37
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        41..53
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        54..59
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
SQ   SEQUENCE   61 AA;  6917 MW;  2A3B2FCE1AA14F5A CRC64;
     FTCFTTPSDT SETCPIGNNI CYEKRWSGHG MQIEKGCVAS CPSFESHYKF LLCCRIENCN
     Q