ID   ANP3_PSEAM              Reviewed;          37 AA.
AC   P02733;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   11-DEC-2019, entry version 50.
DE   RecName: Full=Ice-structuring protein 3;
DE            Short=ISP 3;
DE   AltName: Full=Antifreeze peptide 3;
OS   Pseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Pleuronectiformes; Pleuronectoidei; Pleuronectidae;
OC   Pseudopleuronectes.
OX   NCBI_TaxID=8265;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=588591; DOI=10.1016/0005-2795(77)90395-6;
RA   Devries A.L., Lin Y.;
RT   "Structure of a peptide antifreeze and mechanism of adsorption to ice.";
RL   Biochim. Biophys. Acta 495:388-392(1977).
CC   -!- FUNCTION: Contributes to protect fish blood from freezing at subzero
CC       sea water temperatures. Lowers the blood freezing point. Binds to
CC       nascent ice crystals and prevents further growth.
CC   -!- SIMILARITY: Belongs to the type-I AFP family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; A03192; FDFL3W.
DR   GO; GO:0050825; F:ice binding; IEA:InterPro.
DR   InterPro; IPR000104; Antifreeze_1.
DR   PRINTS; PR00308; ANTIFREEZEI.
PE   1: Evidence at protein level;
KW   Antifreeze protein; Direct protein sequencing; Repeat.
FT   CHAIN           1..37
FT                   /note="Ice-structuring protein 3"
FT                   /id="PRO_0000155148"
SQ   SEQUENCE   37 AA;  3144 MW;  46AA951A962DECA9 CRC64;
     DTASDAAAAA ALTAABAAAA AKLTABBAAA AAAATAA