ANR22_MOUSE
ID ANR22_MOUSE Reviewed; 191 AA.
AC Q9D3J5; Q9CZ89; Q9D3I2;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Ankyrin repeat domain-containing protein 22;
GN Name=Ankrd22;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Head, and Skin;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
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DR EMBL; AK012869; BAB28523.1; -; mRNA.
DR EMBL; AK017360; BAB30707.1; -; mRNA.
DR EMBL; AK017408; BAB30731.1; -; mRNA.
DR EMBL; AK037242; BAC29772.1; -; mRNA.
DR CCDS; CCDS37963.1; -.
DR RefSeq; NP_077166.4; NM_024204.6.
DR AlphaFoldDB; Q9D3J5; -.
DR SMR; Q9D3J5; -.
DR BioGRID; 206333; 1.
DR IntAct; Q9D3J5; 1.
DR STRING; 10090.ENSMUSP00000025686; -.
DR PhosphoSitePlus; Q9D3J5; -.
DR MaxQB; Q9D3J5; -.
DR PaxDb; Q9D3J5; -.
DR PRIDE; Q9D3J5; -.
DR ProteomicsDB; 296314; -.
DR Antibodypedia; 2542; 107 antibodies from 17 providers.
DR DNASU; 52024; -.
DR Ensembl; ENSMUST00000025686; ENSMUSP00000025686; ENSMUSG00000024774.
DR GeneID; 52024; -.
DR KEGG; mmu:52024; -.
DR UCSC; uc008hgb.1; mouse.
DR CTD; 118932; -.
DR MGI; MGI:1277101; Ankrd22.
DR VEuPathDB; HostDB:ENSMUSG00000024774; -.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00390000009005; -.
DR HOGENOM; CLU_121978_0_0_1; -.
DR InParanoid; Q9D3J5; -.
DR OMA; ADPMIKN; -.
DR OrthoDB; 1514637at2759; -.
DR PhylomeDB; Q9D3J5; -.
DR TreeFam; TF332383; -.
DR BioGRID-ORCS; 52024; 3 hits in 73 CRISPR screens.
DR ChiTaRS; Ankrd22; mouse.
DR PRO; PR:Q9D3J5; -.
DR Proteomes; UP000000589; Chromosome 19.
DR RNAct; Q9D3J5; protein.
DR Bgee; ENSMUSG00000024774; Expressed in granulocyte and 74 other tissues.
DR Genevisible; Q9D3J5; MM.
DR Gene3D; 1.25.40.20; -; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR042802; ANR22.
DR PANTHER; PTHR47276; PTHR47276; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13857; Ank_5; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 2: Evidence at transcript level;
KW ANK repeat; Reference proteome; Repeat.
FT CHAIN 1..191
FT /note="Ankyrin repeat domain-containing protein 22"
FT /id="PRO_0000320069"
FT REPEAT 39..68
FT /note="ANK 1"
FT REPEAT 72..100
FT /note="ANK 2"
FT REPEAT 101..130
FT /note="ANK 3"
FT REPEAT 134..163
FT /note="ANK 4"
FT CONFLICT 7
FT /note="E -> D (in Ref. 1; BAB30731)"
FT /evidence="ECO:0000305"
FT CONFLICT 53
FT /note="L -> P (in Ref. 1; BAB28523)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 191 AA; 21910 MW; 4B536AE744100827 CRC64;
MGILYSEPIC QAAYQNDLGQ VWRWAKESNH YVDVQDSFNG DTPLICACRR GHLRIVSFLL
RRNADVNLKN LKERTCLHYA VKKRFTFFDY LLIILLMPVL LIGYFLMVSK TKQNETLVRM
LLNAGVEVNA TDCDGYTALH YACQMKNQTL IPLLLEAHAD PMIKNKHGES SLDIAQRLKF
SQIALMLKRA S
