ANR39_MOUSE
ID ANR39_MOUSE Reviewed; 183 AA.
AC Q9D2X0;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Ankyrin repeat domain-containing protein 39;
GN Name=Ankrd39;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Cecum, and Cerebellum;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the ANKRD39 family. {ECO:0000305}.
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DR EMBL; AK018681; BAB31340.1; -; mRNA.
DR EMBL; AK042896; BAC31398.1; -; mRNA.
DR EMBL; AK160231; BAE35703.1; -; mRNA.
DR CCDS; CCDS14883.1; -.
DR RefSeq; NP_001297462.1; NM_001310533.1.
DR RefSeq; NP_080517.1; NM_026241.4.
DR AlphaFoldDB; Q9D2X0; -.
DR SMR; Q9D2X0; -.
DR STRING; 10090.ENSMUSP00000001172; -.
DR iPTMnet; Q9D2X0; -.
DR PhosphoSitePlus; Q9D2X0; -.
DR EPD; Q9D2X0; -.
DR MaxQB; Q9D2X0; -.
DR PaxDb; Q9D2X0; -.
DR PRIDE; Q9D2X0; -.
DR ProteomicsDB; 281876; -.
DR Antibodypedia; 47508; 75 antibodies from 17 providers.
DR DNASU; 109346; -.
DR Ensembl; ENSMUST00000001172; ENSMUSP00000001172; ENSMUSG00000079610.
DR GeneID; 109346; -.
DR KEGG; mmu:109346; -.
DR UCSC; uc007aqo.1; mouse.
DR CTD; 51239; -.
DR MGI; MGI:1914816; Ankrd39.
DR VEuPathDB; HostDB:ENSMUSG00000079610; -.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00940000160547; -.
DR HOGENOM; CLU_000134_35_1_1; -.
DR InParanoid; Q9D2X0; -.
DR OMA; VQKGTDP; -.
DR OrthoDB; 1453481at2759; -.
DR PhylomeDB; Q9D2X0; -.
DR TreeFam; TF326597; -.
DR BioGRID-ORCS; 109346; 2 hits in 75 CRISPR screens.
DR ChiTaRS; Ankrd39; mouse.
DR PRO; PR:Q9D2X0; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q9D2X0; protein.
DR Bgee; ENSMUSG00000079610; Expressed in rostral migratory stream and 210 other tissues.
DR ExpressionAtlas; Q9D2X0; baseline and differential.
DR Genevisible; Q9D2X0; MM.
DR GO; GO:0030315; C:T-tubule; IBA:GO_Central.
DR GO; GO:0036371; P:protein localization to T-tubule; IBA:GO_Central.
DR GO; GO:0055117; P:regulation of cardiac muscle contraction; IBA:GO_Central.
DR Gene3D; 1.25.40.20; -; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 4.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 1: Evidence at protein level;
KW ANK repeat; Phosphoprotein; Reference proteome; Repeat.
FT CHAIN 1..183
FT /note="Ankyrin repeat domain-containing protein 39"
FT /id="PRO_0000244367"
FT REPEAT 30..59
FT /note="ANK 1"
FT REPEAT 63..92
FT /note="ANK 2"
FT REPEAT 96..125
FT /note="ANK 3"
FT REPEAT 129..158
FT /note="ANK 4"
FT MOD_RES 153
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q53RE8"
SQ SEQUENCE 183 AA; 19639 MW; ACE89F5B115D2B99 CRC64;
MAAPHLCADG SCCSHPSAVP GVQQTLEEMD FDRGIWSAAL NGDLGRVKYF IQKATDPSQP
DSAGYTALHY ASRNGHYAVC QFLLESGAKC DAQTHGGATA LHRASYCGHT EIARLLLSHG
SNPWLVDNDG MTSLHKAAEK GHEDICSLLL QHSPALKAVR DRKARLACDL LPCNSGLWDL
LAS
