ANR44_CHICK
ID ANR44_CHICK Reviewed; 990 AA.
AC Q5F478;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B;
DE Short=PP6-ARS-B;
DE Short=Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B;
DE AltName: Full=Ankyrin repeat domain-containing protein 44;
GN Name=ANKRD44; ORFNames=RCJMB04_2g14;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Putative regulatory subunit of protein phosphatase 6 (PP6)
CC that may be involved in the recognition of phosphoprotein substrates.
CC {ECO:0000250}.
CC -!- SUBUNIT: Protein phosphatase 6 (PP6) holoenzyme is proposed to be a
CC heterotrimeric complex formed by the catalytic subunit, a SAPS domain-
CC containing subunit (PP6R) and an ankyrin repeat-domain containing
CC regulatory subunit (ARS). {ECO:0000250}.
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DR EMBL; AJ851422; CAH65056.1; -; mRNA.
DR RefSeq; NP_001012933.1; NM_001012915.1.
DR AlphaFoldDB; Q5F478; -.
DR SMR; Q5F478; -.
DR STRING; 9031.ENSGALP00000012967; -.
DR PaxDb; Q5F478; -.
DR Ensembl; ENSGALT00000012982; ENSGALP00000012967; ENSGALG00000007996.
DR GeneID; 424055; -.
DR KEGG; gga:424055; -.
DR CTD; 91526; -.
DR VEuPathDB; HostDB:geneid_424055; -.
DR eggNOG; KOG0504; Eukaryota.
DR eggNOG; KOG4177; Eukaryota.
DR GeneTree; ENSGT00950000182908; -.
DR HOGENOM; CLU_000134_58_0_1; -.
DR InParanoid; Q5F478; -.
DR OMA; KCFRKFV; -.
DR OrthoDB; 1115202at2759; -.
DR PhylomeDB; Q5F478; -.
DR PRO; PR:Q5F478; -.
DR Proteomes; UP000000539; Chromosome 7.
DR Bgee; ENSGALG00000007996; Expressed in spleen and 14 other tissues.
DR ExpressionAtlas; Q5F478; baseline and differential.
DR Gene3D; 1.25.40.20; -; 12.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR Pfam; PF12796; Ank_2; 10.
DR Pfam; PF13637; Ank_4; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 28.
DR SUPFAM; SSF48403; SSF48403; 4.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 23.
PE 2: Evidence at transcript level;
KW ANK repeat; Reference proteome; Repeat.
FT CHAIN 1..990
FT /note="Serine/threonine-protein phosphatase 6 regulatory
FT ankyrin repeat subunit B"
FT /id="PRO_0000244573"
FT REPEAT 7..36
FT /note="ANK 1"
FT REPEAT 40..69
FT /note="ANK 2"
FT REPEAT 73..102
FT /note="ANK 3"
FT REPEAT 106..135
FT /note="ANK 4"
FT REPEAT 139..168
FT /note="ANK 5"
FT REPEAT 172..201
FT /note="ANK 6"
FT REPEAT 205..234
FT /note="ANK 7"
FT REPEAT 238..267
FT /note="ANK 8"
FT REPEAT 271..301
FT /note="ANK 9"
FT REPEAT 305..334
FT /note="ANK 10"
FT REPEAT 338..367
FT /note="ANK 11"
FT REPEAT 371..400
FT /note="ANK 12"
FT REPEAT 404..433
FT /note="ANK 13"
FT REPEAT 437..466
FT /note="ANK 14"
FT REPEAT 470..499
FT /note="ANK 15"
FT REPEAT 531..560
FT /note="ANK 16"
FT REPEAT 566..595
FT /note="ANK 17"
FT REPEAT 599..628
FT /note="ANK 18"
FT REPEAT 633..662
FT /note="ANK 19"
FT REPEAT 666..695
FT /note="ANK 20"
FT REPEAT 699..728
FT /note="ANK 21"
FT REPEAT 732..761
FT /note="ANK 22"
FT REPEAT 768..797
FT /note="ANK 23"
FT REPEAT 800..829
FT /note="ANK 24"
FT REPEAT 835..864
FT /note="ANK 25"
FT REPEAT 868..898
FT /note="ANK 26"
FT REPEAT 902..931
FT /note="ANK 27"
FT REPEAT 938..967
FT /note="ANK 28"
SQ SEQUENCE 990 AA; 107398 MW; F97DE42E406967EC CRC64;
MAVLKLADQP PLVQAIFSGD PEEIRMLIYK TEDVNALDAE KRTPLHVASF LGDADIIELL
ILSGARVNAK DNMWLTPLHR AVASRSEEAV QVLIKHSADV NARDKNWQTP LHVAAANKAL
KCAEIIIPML SSVNVSDRGG RTALHHAALN GHVEMVNLLL AKGANINAFD KKDRRALHWA
AYMGHLEVVA LLINHGAEVT CKDKKGYTPL HAAASNGQIN IVKHLLNLGV EIDEMNIYGN
TALHIACYNG QDSVVNELID YGANVNQPNN NGFTPLHFAA ASTHGALCLE LLVNNGADVN
IQSKDGKSPL HMTAVHGRFT RSQTLIQNGG EIDCVDKDGN TPLHVAARYG HELLINTLIT
SGADTAKCGI HNMFPLHLAA LNAHSDCCRK LLSSGFEIDT PDSFGRTCLH AAAAGGNVEC
IKLLQSSGAD FNKKDKRGRT PLHYAAANCH FHCIETLVTT GANINETDDW GRTPLHYAAA
SDMDRKKNIL GNSHENAEEL ERTSEMKEKE AALCLEFLLQ NDANPSIQDK EGYNTVHYAA
AYGHRQCLEL LLEKNSNMFE ESDSSATKSP LHLAAYNGHH QALEVLLQSL VDLDIKDEKG
RTALDLAAFK GHAECVEALI SQGASVTVKD NVTKRTPLHA SVINGHTPCL RLLLEVADNP
DVTDAKGQTP LMLAVAYGHI DAVSLLLEKE ASVDAADLLG CTALHRGIMT GHEECVQMLL
EKEVSILCKD ARGRTPLHFA AARGHATWLS ELLQIALSEE DCSLKDNQGY TPLHWACYNG
HENCIEVLLE QKFFRKFYGN SFSPLHCAVI NDHENCASML IGAIDASIVN CKDDKGRTPL
HAAAFADHVE CLQLLLSHSA QVNAVDHAGK TALMMAAQNG HVGAVDFLVN IAKADLTLRD
KDSNTSLHLA SSKGHEKCAL LILDKIQEQS LINAKNNSLQ TPLHIAARNG LKMVVEELLA
KGACVLAVDE NVSRSNGPRT SSATDVQKEE
